Home Chemistry Heterocyclic Building Blocks Pyrrolidines 3-Bromopyrrolidine
Nucleophilic Substitution: The bromine atom can undergo nucleophilic substitution reactions with various nucleophiles to form substituted pyrrolidine derivatives.
Alkylation: The nitrogen atom can be alkylated by reaction with alkyl halides or sulfonates.
Substitution Reactions: The bromine atom can undergo substitution reactions, such as nucleophilic substitution or electrophilic substitution.
Reduction: The bromine atom can be replaced with a hydrogen atom through reduction reactions using appropriate reducing agents.
Ring-opening Reactions: The pyrrolidine ring may undergo ring-opening reactions under certain conditions, leading to the formation of linear or branched compounds.
Cross-Coupling Reactions: The bromine atom can participate in cross-coupling reactions, such as Suzuki coupling or Heck coupling, to form biaryl or heteroaryl compounds.
Halogenation: The hydrogen atoms on the pyrrolidine ring can be replaced with halogen atoms through halogenation reactions.
Nucleophilic Addition: The double bond of the pyrrolidine ring can undergo nucleophilic addition reactions with nucleophiles.
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(S)-tert-Butyl 3-bromopyrrolidine-1-carboxylate
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(3R,4R)-tert-Butyl 3-bromo-4-hydroxypyrrolidine-1-carboxylate
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tert-Butyl 3-bromopyrrolidine-1-carboxylate
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