Home Chemistry Organic Building Blocks Fluorinated Building Blocks 2,6-Difluorobenzaldehyde
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —F,—CHO).
Electrophilic Aromatic Substitution (EAS): Fluorobenzene can undergo typical electrophilic aromatic substitution reactions, similar to benzene. The fluorine atom, being electron-withdrawing, can influence the reactivity of the benzene ring. Common EAS reactions include nitration, halogenation, sulfonation, and Friedel-Crafts reactions.
Schiff Base Formation: Benzaldehyde can react with primary 【amines|https://www.ambeed.com/amines.html】 to form Schiff bases, which are important intermediates in organic synthesis.
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(E)-Methyl 3-(3,5-difluoro-4-formylphenyl)acrylate
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4-Bromo-2,3,5,6-tetrafluorobenzaldehyde
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