Home Chemistry Organic Building Blocks Alkynyls 1,4-Diphenylbuta-1,3-Diyne
Halogenation: 1,4-diphenylbuta-1,3-diyne can undergo halogenation reactions with halogens like chlorine or bromine to add halogen atoms to the triple bonds. For example, you can have the addition of two halogen atoms, one to each triple bond, leading to the formation of 1,4-diphenyl-2,5-dihalopenta-1,3-dienes.
Hydrogenation: Catalytic hydrogenation can reduce the triple bonds in the butadiyne system to form 1,4-diphenylbuta-1,3-diene, which has double bonds instead of triple bonds.
Metal-Catalyzed Cross-Coupling Reactions: You can perform cross-coupling reactions like Suzuki-Miyaura or Heck reactions to introduce various substituents onto the phenyl rings.
Oxidation: You can oxidize the alkyne to form the corresponding diketone. Oxidation could be achieved using strong oxidizing agents like potassium permanganate (KMnO4).
Sonogashira Reaction: 1,4-diphenylbuta-1,3-diyne can participate in Sonogashira coupling reactions with aryl or alkyl halides in the presence of a palladium catalyst and a base to form substituted alkynes.
Reduction: You can reduce the alkyne using a reducing agent like lithium aluminum hydride (LiAlH4) to obtain the corresponding alkene.
Ring-Opening Reactions: Under certain conditions, the triple bonds can undergo ring-opening reactions to form open-chain compounds.
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4,4'-(Buta-1,3-diyne-1,4-diyl)dibenzoic acid
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4,4'-(Buta-1,3-diyne-1,4-diyl)dibenzaldehyde
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2,2'-(Buta-1,3-diyne-1,4-diyl)dianiline
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5,5'-(Buta-1,3-diyne-1,4-diyl)diisophthalic acid
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