Chemistry Heterocyclic Building Blocks Naphthyridines

Naphthyridines

Naphthyridine, which has a chemical formula of C8H6N2, belongs to a group of diazanaphthalenes called isomeric naphthyridines. This particular naphthyridine is the most extensively researched among the six isomers.

There are various marine products that contain functionalized naphthyridines and their benzo/heterofused analogs. These compounds have been found to exhibit diverse properties, including anti-proliferative and anti-aggressive effects, as well as inhibition of HIV-1 integrase. Additionally, they are employed as anti-HCV agents.

Due to the presence of nitrogen atoms, the naphthyridines exhibit electron drift in their molecular orbitals, resulting in distortion of each of the five orbitals. These orbitals contain 10 delocalized π-electrons.

More >>

Further Reading:
>>
More Skeleton screening
✕ ✕ ✕ ✕ ✕ ✕

Framework+−

1,5-naphthyridine-3-carboxylic acid 1,6-naphthyridine 1,7-naphthyridine 2,7-naphthyridine 3-bromo-1,5-naphthyridine 4-bromo-1,5-naphthyridine 4-chloro-1,5-naphthyridine 5,6,7,8-tetrahydro-1,6-naphthyridine 5,6,7,8-tetrahydro-1,7-naphthyridine

By Key Group+−

bromo-naphthyridin-one bromo-naphthyridine chloro-naphthyridin-one chloro-naphthyridine fluoro-naphthyridine hydroxy-naphthyridine methoxy-naphthyridine methyl-naphthyridine naphthyridin-amine naphthyridin-one naphthyridine hydrochloride naphthyridine-carboxylate naphthyridine-carboxylic acid pyridonaphthyridine tetrahydronaphthyridin

By Parent Nucleus+−

Aromatic Heterocycles Azetidines

By Functional Group+−

Alcohols Amides Amidines Amines Aryls Bromides Carboxylic Acids Chiral Building Blocks Chlorides Esters Ethers Fluorinated Building Blocks Ketones Phenols

By Chemical Elements+−

    Bx
    Cx
    Nx
    Ox
    Fx
    Six
    Px
    Sx
    Clx
    Brx
    Ix

    Formula Weight+−

    cLogP+−

    H-Acceptors+−

    H-Donors+−

    Polar Surface Area+−

    Druglikeness+−

    NNCH/NNH+−

    sp3-Atoms+−

    Non-Aromatic Rings+−

    Aromatic Rings+−

    Rotatable Bonds+−

    By Configuration+−

    tert-Butyl 7-chloro-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate

    click to sign in and save

    A1181404679392-23-598%

    tert-Butyl 7-chloro-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate

    $64.00/5g

    Detail
    1,5-Naphthyridine

    click to sign in and save

    A163920254-79-598%

    1,5-Naphthyridine

    $27.00/5g

    Detail
    tert-Butyl (8-chloro-1,7-naphthyridin-3-yl)carbamate

    click to sign in and save

    A14423022708286-96-698%

    tert-Butyl (8-chloro-1,7-naphthyridin-3-yl)carbamate

    $1233.00/1g

    Detail
    1,2,3,4-Tetrahydro-2,6-naphthyridine dihydrochloride

    click to sign in and save

    A119231449175-43-397%

    1,2,3,4-Tetrahydro-2,6-naphthyridine dihydrochloride

    $114.00/250mg

    Detail
    tert-Butyl 2-(Hydroxymethyl)-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate

    click to sign in and save

    A8355031868106-31-398%

    tert-Butyl 2-(Hydroxymethyl)-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate

    $320.00/250mg

    Detail
    2-NP

    click to sign in and save

    A52245065182-56-198%

    2-NP

    $795.00/250mg

    Detail
    Torin 2

    click to sign in and save

    A1074331223001-51-198%

    Torin 2

    $17.00/5mg

    Detail
    2-Bromo-3-chloro-1,8-naphthyridine

    click to sign in and save

    A99605752626-32-195%

    2-Bromo-3-chloro-1,8-naphthyridine

    $672.00/1g

    Detail
    7-Chloro-2,6-naphthyridin-1(2H)-one

    click to sign in and save

    A10052991393568-79-097%

    7-Chloro-2,6-naphthyridin-1(2H)-one

    $670.00/1g

    Detail
    5,7-Bis(trifluoromethyl)-1,8-naphthyridin-2-amine

    click to sign in and save

    A86028351420-72-595%

    5,7-Bis(trifluoromethyl)-1,8-naphthyridin-2-amine

    $30.00/250mg

    Detail
    1,8-Naphthyridin-2-amine

    click to sign in and save

    A28895315992-83-397%

    1,8-Naphthyridin-2-amine

    $24.00/250mg

    Detail
    AMG-337

    click to sign in and save

    A1031521173699-31-498+%

    AMG-337

    $113.00/10mg

    Detail
    2,4-Bis(trifluoromethyl)imidazo[1,2-a][1,8]naphthyridine-8-carbohydrazide

    click to sign in and save

    A888503691868-81-290%

    2,4-Bis(trifluoromethyl)imidazo[1,2-a][1,8]naphthyridine-8-carbohydrazide

    $672.00/1g

    Detail
    2-Methyl-1,7-naphthyridin-8(7H)-one

    click to sign in and save

    A236809930303-53-097%

    2-Methyl-1,7-naphthyridin-8(7H)-one

    $277.00/250mg

    Detail
    6-Methoxy-1,5-naphthyridin-4-ol

    click to sign in and save

    A12988323443-25-696%

    6-Methoxy-1,5-naphthyridin-4-ol

    $60.00/250mg

    Detail
    4-(6-(Azetidin-1-yl)-2-methyl-1-oxo-1,2-dihydro-2,7-naphthyridin-4-yl)-2,6-dimethoxybenzaldehyde

    click to sign in and save

    A13884752460248-49-998%

    4-(6-(Azetidin-1-yl)-2-methyl-1-oxo-1,2-dihydro-2,7-naphthyridin-4-yl)-2,6-dimethoxybenzaldehyde

    $231.00/100mg

    Detail
    6-Amino-8-bromo-1,7-naphthyridine

    click to sign in and save

    A2388995912-35-697%

    6-Amino-8-bromo-1,7-naphthyridine

    $45.00/100mg

    Detail
    5,7-Dichloro-1,8-naphthyridin-2-amine

    click to sign in and save

    A145208131998-24-895%

    5,7-Dichloro-1,8-naphthyridin-2-amine

    $134.00/250mg

    Detail
    5,6,7,8-Tetrahydro-1,6-naphthyridine-3-carbonitrile hydrochloride

    click to sign in and save

    A16275392901082-00-495%

    5,6,7,8-Tetrahydro-1,6-naphthyridine-3-carbonitrile hydrochloride

    $238.00/50mg

    Detail
    1,7-Naphthyridin-4(1H)-one

    click to sign in and save

    A11790060122-51-297%

    1,7-Naphthyridin-4(1H)-one

    $281.00/250mg

    Detail
    1 2 3 4 5 6 7 8 9 ...    page 1 of 51 Pages

    Inquiry