Chemistry Heterocyclic Building Blocks Benzimidazoles

Benzimidazoles

Benzimidazole is a white solid that occurs in the form of tabular crystals. This bicyclic compound can be visualized as fused rings of the aromatic compounds benzene and imidazole.

One of the commonly utilized ring systems for small molecule drugs approved by the United States Food and Drug Administration is the benzimidazole derivatives.

Benzimidazole finds application as an organic solderability preservative in the manufacturing of printed circuit boards, and it is also a source of various dyes derived from this compound.

The benzimidazole ring is highly stable and remains unaffected by concentrated sulfuric acid even when heated under pressure to 270°C. It also withstands vigorous treatment with hot hydrochloric acid or alkalis without any apparent changes.

Under harsh conditions, oxidation can cause cleavage of the benzene ring in benzimidazole. Furthermore, the benzimidazole ring system exhibits significant resistance to reduction, except for a few catalytic reduction techniques.

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(1H-benzo[d]imidazol-2-yl)methanamine (1H-benzo[d]imidazol-2-yl)methanol 1,2-diphenyl-1H-benzo[d]imidazole 1-benzyl-1H-benzo[d]imidazole 1-ethyl-1H-benzo[d]imidazole 1-methyl-1H-benzo[d]imidazole 1-phenyl-1H-benzo[d]imidazole 1H-benzo[d]imidazol-2-amine 1H-benzo[d]imidazol-5-amine 1H-benzo[d]imidazol-6-amine 1H-benzo[d]imidazole-2-carbaldehyde 1H-benzo[d]imidazole-2-carboxylic acid 1H-benzo[d]imidazole-2-thiol 1H-benzo[d]imidazole-4-carboxylic acid 1H-benzo[d]imidazole-5-carboxylic acid 2-((pyridin-2-ylmethyl)thio)-1H-benzo[d]imidazole 2-(1H-benzo[d]imidazol-2-yl)ethan-1-amine 2-(chloromethyl)-1H-benzo[d]imidazole 2-benzyl-1H-benzo[d]imidazole 2-bromo-1H-benzo[d]imidazole 2-chloro-1H-benzo[d]imidazole 2-methyl-1H-benzo[d]imidazole 4-bromo-1H-benzo[d]imidazole 4-methyl-1H-benzo[d]imidazole 5,6-dichloro-1H-benzo[d]imidazole 5-bromo-1H-benzo[d]imidazole 5-chloro-1H-benzo[d]imidazole 5-methoxy-1H-benzo[d]imidazole 5-methyl-1H-benzo[d]imidazole 6-chloro-1H-benzo[d]imidazole methyl (1H-benzo[d]imidazol-2-yl)carbamate methyl 1H-benzo[d]imidazole-2-carboxylate tert-butyl 1H-benzo[d]imidazole-1-carboxylate

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benzimidazol-amine Benzimidazole Derivatives benzimidazole-carboxylate benzimidazole-carboxylic acid benzimidazole-hydrochloride benzimidazole-nitrile benzoimidazol-methanamine benzoimidazol-methanol benzoimidazol-one benzoimidazole-thione benzyl-benzoimidazole bromo-benzimidazole chloro-benzimidazole dimethyl-benzoimidazole dioxaborolane-benzimidazole fluoro-benzoimidazole hydroxy-benzimidazole methoxy-benzoimidazole methylbenzimidazole nitro-benzoimidazole other-benzimidazole phenyl-benzoimidazole piperidine-benzimidazole pyridin-benzoimidazole trifluoromethyl-benzimidazole

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Aromatic Heterocycles Other Aliphatic Heterocycles Oxadiazoles Piperazines Piperidines Pyridines Pyrimidines Pyrroles Tetrahydropyrans Thiophenols

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Alcohols Aldehydes Alkenyls Amides Amines Aryls Bromides Carboxylic Acids Chiral Building Blocks Chlorides Difluoromethyls Esters Ethers Fluorinated Building Blocks Hydrazines Iodides Nitriles Nitroes Organoboron Phenols Sulfamides Sulfides Sulfonic Acids Sulfoxides Trifluoromethyls

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    (1H-Benzo[d]imidazol-2-yl)(phenyl)methanamine dihydrochloride

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    (1H-Benzo[d]imidazol-2-yl)(phenyl)methanamine dihydrochloride

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    6-Fluoro-1H-benzo[d]imidazole-4-carboxylic acid

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    6-Fluoro-1H-benzo[d]imidazole-4-carboxylic acid

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    (5-(Trifluoromethyl)-1H-benzo[d]imidazol-2-yl)methanol

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    (5-(Trifluoromethyl)-1H-benzo[d]imidazol-2-yl)methanol

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    4-(1H-Benzo[d]imidazol-1-yl)benzoic acid hydrochloride

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    4-(1H-Benzo[d]imidazol-1-yl)benzoic acid hydrochloride

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    5-Bromo-1-phenyl-1H-benzo[d]imidazole

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    5-Bromo-1-phenyl-1H-benzo[d]imidazole

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    Methyl 6-(trifluoromethoxy)-1H-benzo[d]imidazole-2-carboxylate

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    Methyl 6-(trifluoromethoxy)-1H-benzo[d]imidazole-2-carboxylate

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    Mibefradil 2HCl

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    Mibefradil 2HCl

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    6-(2-Chloro-5-fluoropyrimidin-4-yl)-1-cyclopropyl-4-fluoro-2-methyl-1H-benzo[d]imidazole

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    A12461661231930-43-098%

    6-(2-Chloro-5-fluoropyrimidin-4-yl)-1-cyclopropyl-4-fluoro-2-methyl-1H-benzo[d]imidazole

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    2-(2-((2-(2-Fluorophenoxy)ethyl)thio)-1H-benzo[d]imidazol-1-yl)acetic acid

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    2-(2-((2-(2-Fluorophenoxy)ethyl)thio)-1H-benzo[d]imidazol-1-yl)acetic acid

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    Methyl 6-amino-7-fluoro-1H-benzo[d]imidazole-5-carboxylate

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    Methyl 6-amino-7-fluoro-1H-benzo[d]imidazole-5-carboxylate

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    2-Isopropyl-1H-benzo[d]imidazole-5-carboxylic acid hydrochloride

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    2-Isopropyl-1H-benzo[d]imidazole-5-carboxylic acid hydrochloride

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    2-Chlorobenzimidazole

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    2-Chlorobenzimidazole

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    2-Methyl-1H-benzoimidazol-5-ylamine

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    2-Methyl-1H-benzoimidazol-5-ylamine

    $791.00/25g

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    2-Chloro-5-methoxy-1H-benzo[d]imidazole

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    2-Chloro-5-methoxy-1H-benzo[d]imidazole

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    2-Amino-1-isopropylbenzimidazole

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    A13939590871-47-995%

    2-Amino-1-isopropylbenzimidazole

    $220.00/5g

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    2,6,7-Trichloro-1H-benzo[d]imidazole

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    A1146672142356-71-698%

    2,6,7-Trichloro-1H-benzo[d]imidazole

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    Ethyl 2-ethoxy-1-((2'-(N'-hydroxycarbamimidoyl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylate

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    A7760051397836-41-799%

    Ethyl 2-ethoxy-1-((2'-(N'-hydroxycarbamimidoyl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylate

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    Emedastine difumarate

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    Emedastine difumarate

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    2-((Methoxycarbonyl)amino)-1H-benzo[d]imidazole-5-carboxylic acid

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    2-((Methoxycarbonyl)amino)-1H-benzo[d]imidazole-5-carboxylic acid

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    N,1-Dimethyl-1H-benzo[d]imidazol-2-amine

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    N,1-Dimethyl-1H-benzo[d]imidazol-2-amine

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