Home Chemistry Heterocyclic Building Blocks Pyrrolidines 3,3-Difluoropyrrolidine
Ring-opening reactions: The cyclic structure of 3,3-difluoropyrrolidine may undergo ring-opening reactions under certain conditions to form linear or branched compounds.
Substitution reactions: The fluorine atoms on the pyrrolidine ring can undergo substitution reactions, such as nucleophilic substitution or electrophilic substitution.
Cyclization reactions: 3,3-difluoropyrrolidine can participate in cyclization reactions to form cyclic compounds or larger molecules.
Functional group transformations: The fluorine atoms can be replaced with other functional groups through appropriate chemical reactions.
Reduction: The pyrrolidine ring can be reduced to form saturated derivatives.
Oxidation: 3,3-difluoropyrrolidine can undergo oxidation reactions under suitable conditions.
Alkylation: The nitrogen atom can be alkylated by reaction with alkyl halides or sulfonates.
Halogenation: The hydrogen atoms on the pyrrolidine ring can be replaced with halogen atoms through halogenation reactions.
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tert-Butyl 3,3-difluoro-4-hydroxypyrrolidine-1-carboxylate
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tert-Butyl 4-amino-3,3-difluoropyrrolidine-1-carboxylate
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tert-Butyl (4S)-3,3-difluoro-4-hydroxypyrrolidine-1-carboxylate
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(S)-tert-Butyl 2-carbamoyl-4,4-difluoropyrrolidine-1-carboxylate
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(S)-4,4-Difluoropyrrolidine-2-carboxamide hydrochloride
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(S)-1-(tert-Butoxycarbonyl)-4,4-difluoro-2-methylpyrrolidine-2-carboxylic acid
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(S)-4,4-Difluoropyrrolidine-2-carbonitrile hydrochloride
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3,3,4,4-Tetrafluoropyrrolidine hydrochloride
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(S)-4,4-Difluoro-2-(fluoromethyl)pyrrolidine hydrochloride
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4,4-Difluoropyrrolidin-3-ol hydrochloride
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3,3-Difluoropyrrolidine-1-sulfonyl chloride
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1-tert-Butyl 2-methyl 3,3-difluoropyrrolidine-1,2-dicarboxylate
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(S)-1-(2-Aminoacetyl)-4,4-difluoropyrrolidine-2-carbonitrile hydrochloride
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