Home Chemistry Organic Building Blocks Bromides 2-Bromo-1-Fluoro-4-Methylbenzene
These compounds have the same murcko framework: benzene,and at least 3 kinds of functional groups( —Br,—F,—CH3).
Electrophilic Aromatic Substitution (EAS): Bromobenzene can react with electrophiles in substitution reactions, such as nitration, sulfonation, halogenation, and Friedel-Crafts acylation/alkylation.
Metalation Reactions: Fluorobenzene can undergo metalation reactions, where a metal species (such as an organolithium or organomagnesium compound) replaces a hydrogen atom on the benzene ring. These metalated intermediates can then be used in various synthetic transformations.
Halogenation: Toluene can undergo halogenation reactions with halogens (such as chlorine or bromine) in the presence of a catalyst or under UV light. The hydrogen atoms on the benzene ring can be replaced by halogen atoms, resulting in the formation of mono-, di-, or polyhalogenated derivatives of toluene.
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Methyl 4-bromo-5-fluoro-2-methylbenzoate
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1-Bromo-4-chloro-2-fluoro-5-methylbenzene
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1-Bromo-2-fluoro-5-methyl-4-nitrobenzene
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(3-Bromo-2-fluoro-5-methylphenyl)boronic acid
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3-Bromo-2-fluoro-5-methylbenzonitrile
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