Home Chemistry Organic Building Blocks Iodides 1-Iodo-2-(Trifluoromethyl)Benzene
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —I,—CF3).
Metalation Reactions: Iodobenzene can undergo metalation reactions, where a metal species (such as an organolithium or organomagnesium compound) replaces a hydrogen atom on the benzene ring. These metalated intermediates can then be used in various synthetic transformations.
Oxidation: Oxidation reactions could lead to the conversion of the trifluoromethyl group to a carbonyl group (e.g., trifluoromethyl ketone).
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