Diazirines

Diazirines are compact, photoactivatable groups commonly used in chemical biology to study protein interactions. Upon UV irradiation (typically ~350 nm), the diazirine ring forms a reactive carbene intermediate that rapidly inserts into nearby C–H, N–H, or O–H bonds, enabling covalent crosslinking of transient protein–protein or protein–ligand interactions. This makes them powerful tools for target identification and interactome mapping in live-cell environments.

Diazirines

3-(4-Bromophenyl)-3-(trifluoromethyl)-3H-diazirine
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A136108952143-02-195%

3-(4-Bromophenyl)-3-(trifluoromethyl)-3H-diazirine

$85.00/100mg Detail

4-[3-(Trifluoromethyl)-3H-diazirin-3-yl]benzenemethanamine HCl
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A9520551258874-29-198%

4-[3-(Trifluoromethyl)-3H-diazirin-3-yl]benzenemethanamine HCl

$61.00/100mg Detail

4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)benzoic acid
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A68084685559-46-297%

4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)benzoic acid

$269.00/1g Detail

4-[3-(Trifluoromethyl)-3H-diazirin-3-yl]benzyl Alcohol
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A33665987736-88-796%

4-[3-(Trifluoromethyl)-3H-diazirin-3-yl]benzyl Alcohol

$49.00/100mg Detail

3-(4-(Bromomethyl)phenyl)-3-(trifluoromethyl)-3H-diazirine
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A21159192367-11-895%

3-(4-(Bromomethyl)phenyl)-3-(trifluoromethyl)-3H-diazirine

$119.00/100mg Detail

3-(3-(Trifluoromethyl)-3H-diazirin-3-yl)phenol
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A790861113787-85-295%

3-(3-(Trifluoromethyl)-3H-diazirin-3-yl)phenol

$293.00/50mg Detail

(3-(3-(Trifluoromethyl)-3H-diazirin-3-yl)phenyl)methanol
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A1186652176640-04-395%

(3-(3-(Trifluoromethyl)-3H-diazirin-3-yl)phenyl)methanol

$63.00/100mg Detail

4-[3-(Trifluoromethyl)diazirin-3-yl] benzoic acid N-hydroxysuccinimide ester
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A42187287736-89-897%

4-[3-(Trifluoromethyl)diazirin-3-yl] benzoic acid N-hydroxysuccinimide ester

$106.00/100mg Detail

4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)benzaldehyde
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A566499128886-88-495%

4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)benzaldehyde

$86.00/50mg Detail

3-(4-Iodophenyl)-3-(trifluoromethyl)-3H-diazirine
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A110477210107-38-397%

3-(4-Iodophenyl)-3-(trifluoromethyl)-3H-diazirine

$997.00/1g Detail

3-(4-(Iodomethyl)phenyl)-3-(trifluoromethyl)-3H-diazirine
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A118664795758-92-295%

3-(4-(Iodomethyl)phenyl)-3-(trifluoromethyl)-3H-diazirine

$260.00/1g Detail

3-(3-(Trifluoromethyl)-3H-diazirin-3-yl)benzoic acid
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A152022176389-60-997%

3-(3-(Trifluoromethyl)-3H-diazirin-3-yl)benzoic acid

$324.00/1g Detail

3-(3-Bromophenyl)-3-(trifluoromethyl)-3H-diazirine
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A443704142719-82-295%

3-(3-Bromophenyl)-3-(trifluoromethyl)-3H-diazirine

$1039.00/1g Detail

3-Phenyl-3-(trifluoromethyl)-3H-diazirine
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A14027273899-14-690%

3-Phenyl-3-(trifluoromethyl)-3H-diazirine

$123.00/1g Detail

2-(3-(3-(Trifluoromethyl)-3H-diazirin-3-yl)phenyl)acetic acid
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A15506661627712-50-895%

2-(3-(3-(Trifluoromethyl)-3H-diazirin-3-yl)phenyl)acetic acid

$1318.00/1g Detail

2-Hydroxy-4-[3-(trifluoromethyl)-3H-diazirin-3-yl]benzaldehyde
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A800266308085-25-897%

2-Hydroxy-4-[3-(trifluoromethyl)-3H-diazirin-3-yl]benzaldehyde

$714.00/100mg Detail

2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol
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A1181471450754-41-297%

2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol

$617.00/1g Detail

2-(3-(But-3-yn-1-yl)-3H-diazirin-3-yl)ethan-1-amine
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A1072481450752-97-297%

2-(3-(But-3-yn-1-yl)-3H-diazirin-3-yl)ethan-1-amine

$87.00/25mg Detail

3-(3-(But-3-yn-1-yl)-3H-diazirin-3-yl)propan-1-amine
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A8493591450754-37-695%

3-(3-(But-3-yn-1-yl)-3H-diazirin-3-yl)propan-1-amine

$126.00/10mg Detail

3-(2-Bromoethyl)-3-(but-3-yn-1-yl)-3H-diazirine
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A16838102432830-88-995%

3-(2-Bromoethyl)-3-(but-3-yn-1-yl)-3H-diazirine

$176.00/25mg Detail

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