Home Chemistry Heterocyclic Building Blocks Pyridines Picolinic Acid
Esterification: Picolinic acid can undergo esterification reactions with alcohols in the presence of acid catalysts to form picolinate esters.
Amidation: Picolinic acid can react with amines to form amides through amidation reactions.
Metal Complexation: The nitrogen atom of the pyridine ring in picolinic acid can coordinate with transition metal ions to form metal complexes. This property is often exploited in coordination chemistry and metal ion extraction processes.
Oxidation: Picolinic acid can be oxidized to form various products depending on the reaction conditions and oxidizing agents used.
Halogenation: Picolinic acid can undergo halogenation reactions, such as chlorination or bromination, leading to the introduction of halogen atoms onto the pyridine ring or the carboxylic acid group.
Substitution Reactions: The aromatic ring in picolinic acid can undergo electrophilic aromatic substitution reactions, leading to the substitution of hydrogen atoms with various functional groups.
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5-Fluoropyridine-2,3-dicarboxylic acid hydrochloride
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6-(((tert-Butoxycarbonyl)amino)methyl)picolinic acid
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3-Methoxy-6-(trifluoromethyl)picolinic acid
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6-(Trifluoromethyl)pyridine-2,3-dicarboxylic acid
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5-((tert-Butoxycarbonyl)amino)picolinic acid
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3-Hydroxy-5-(trifluoromethyl)picolinic acid
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