Home Chemistry Organic Building Blocks Difluoromethyls 1-(Difluoromethoxy)-2-Fluorobenzene
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —F,—OCHF2).
Metalation Reactions: Fluorobenzene can undergo metalation reactions, where a metal species (such as an organolithium or organomagnesium compound) replaces a hydrogen atom on the benzene ring. These metalated intermediates can then be used in various synthetic transformations.
Base-Catalyzed Reactions: The methoxy group could be deprotonated by a strong base, leading to potential reactions involving the negatively charged oxygen atom.
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3-(Difluoromethoxy)-2,6-difluorobenzoic acid
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(4-(Difluoromethoxy)-3,5-difluorophenyl)boronic acid
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1-(Difluoromethoxy)-2-fluoro-4-nitrobenzene
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3-(Difluoromethoxy)-4-fluorobenzaldehyde
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(4-(Difluoromethoxy)-3-fluorophenyl)methanol
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4-(Difluoromethoxy)-3-fluorobenzonitrile
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4-Bromo-1-(difluoromethoxy)-2-fluorobenzene
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4-Bromo-2-(difluoromethoxy)-1-fluorobenzene
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