Chemistry
Organic Building Blocks
Hydrazides
Hydrazides, in the realm of organic chemistry, are a category of organic compounds denoted by the formula RNHNH2, where R represents acyl (R'CO-), sulfonyl (R'SO2-), or phosphoryl (R'2P(O)-) groups.
Hydrazide analogues exhibit diverse biological activities, including but not limited to antidepressant, anticonvulsant, anti-inflammatory, antibacterial, antimalarial, anticancer, and antimicrobial properties.
Hydrazides are typically synthesized through the reaction of acid derivatives, such as esters, acid chlorides, or amides, with hydrazine.
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(S)-tert-Butyl (1-hydrazinyl-1-oxo-3-phenylpropan-2-yl)carbamate
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tert-Butyl 2-(2,5-difluorobenzoyl)hydrazinecarboxylate