Home Chemistry Organic Building Blocks Bromides 3-Bromo-2-Fluorobenzaldehyde
These compounds have the same murcko framework: benzene,and at least 3 kinds of functional groups( —Br,—F,—CHO).
Grignard Reaction: Bromobenzene can react with a Grignard reagent (organomagnesium compound) to form a new carbon-carbon bond, leading to the introduction of various functional groups.
Metalation Reactions: Fluorobenzene can undergo metalation reactions, where a metal species (such as an organolithium or organomagnesium compound) replaces a hydrogen atom on the benzene ring. These metalated intermediates can then be used in various synthetic transformations.
Wittig Reaction: Benzaldehyde can react with a phosphonium ylide in the presence of a base to form olefins (【alkenes|https://www.ambeed.com/alkenyls.html】) through the Wittig reaction.
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