Chemistry Heterocyclic Building Blocks Pyrazoles 1-(Tetrahydro-2H-Pyran-4-Yl)-1H-Pyrazole

1-(Tetrahydro-2H-Pyran-4-Yl)-1H-Pyrazole

Alkylation: The compound can undergo alkylation reactions where alkyl halides or other alkylating agents react with the nitrogen in the pyrazole ring or the oxygen in the tetrahydro-2H-pyran ring. Aldol Reaction: If there are appropriate functional groups nearby, an aldol reaction may occur, leading to the formation of a new carbon-carbon bond. Oxidation: The tetrahydro-2H-pyran ring can be oxidized to form a corresponding ketone. Reduction: The compound can undergo reduction reactions if there are suitable reducing agents present, potentially converting functional groups like ketones to alcohols. Cyclization: Depending on the reaction conditions and the presence of other functional groups, intramolecular cyclization reactions can take place, leading to the formation of cyclic compounds. Substitution Reactions: If there are leaving groups present on the compound, substitution reactions, such as nucleophilic aromatic substitution (SNAr) or other substitution reactions, can occur. Grignard Reaction: The compound can react with Grignard reagents to form new carbon-carbon bonds. Heterocyclic Chemistry: Given the presence of the pyrazole ring, it can participate in various heterocyclic chemistry reactions, including ring-opening and ring-closing reactions.

Further Reading:

Framework+−

(1-Methyl-1H-Pyrazol-3-Yl)Methanol (1-Phenyl-1H-Pyrazol-4-Yl)Boronic Acid 1,3-Dimethyl-1H-Pyrazole 1,3-Diphenyl-1H-Pyrazole 1,4,5,6-Tetrahydropyrrolo[3,4-C]Pyrazole 1,5-Diphenyl-1H-Pyrazole 1-(2-Chlorophenyl)-1H-Pyrazole 1-(3-Chlorophenyl)-1H-Pyrazole 1-(4-Methoxybenzyl)-1H-Pyrazole 1-(Azetidin-3-Yl)-1H-Pyrazole 1-(Tetrahydro-2H-Pyran-2-Yl)-1H-Pyrazole 1-(Tetrahydro-2H-Pyran-4-Yl)-1H-Pyrazole 1-Benzyl-1H-Pyrazolo[3,4-B]Pyridine 1-Benzyl-4-Bromo-1H-Pyrazole 1-Benzyl-4-Iodo-1H-Pyrazole 1-Cyclopentyl-1H-Pyrazole 1-Cyclopropyl-1H-Pyrazole 1-Methyl-1H-Pyrazol-3-Amine 1-Methyl-3-Phenyl-1H-Pyrazole 1-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole 1-Methyl-5-Phenyl-1H-Pyrazole 1-Phenyl-1H-Pyrazol-3-Amine 1-Phenyl-1H-Pyrazol-3-Ol 1-Phenyl-1H-Pyrazol-5-Amine 1-Phenyl-1H-Pyrazole-3-Carboxylic Acid 1-Phenyl-1H-Pyrazole-4-Carbaldehyde 1-Phenyl-1H-Pyrazole-4-Carbonitrile 1-Phenyl-1H-Pyrazole-4-Carboxylic Acid 1-Phenyl-1H-Pyrazole-5-Carboxylic Acid 1-Phenyl-3-(Trifluoromethyl)-1H-Pyrazole 1-Trityl-1H-Pyrazole 1H-Pyrazol-4-Amine 1H-Pyrazol-4-Ol 1H-Pyrazol-5-Amine 1H-Pyrazole-4-Carbaldehyde 1H-Pyrazole-4-Carbonitrile 1H-Pyrazole-4-Carboxylic Acid 1H-Pyrazole-4-Sulfonyl Chloride 1H-Pyrazole-5-Carboxamide 1H-Pyrazole-5-Carboxylic Acid 1H-Pyrazolo[3,4-B]Pyrazine 1H-Pyrazolo[3,4-B]Pyridin-5-Amine 1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine 1H-Pyrazolo[4,3-D]Pyrimidine 2,3-Dihydropyrazolo[5,1-B]Oxazole 2,4-Dihydro-3H-Pyrazol-3-One 2,6-Di(1H-Pyrazol-1-Yl)Pyridine 2-(1H-Pyrazol-1-Yl)Pyridine 2-(1H-Pyrazol-1-Yl)Pyrimidine 2-(1H-Pyrazol-3-Yl)Pyridine 2-Phenyl-2,4-Dihydro-3H-Pyrazol-3-One 3-(Tert-Butyl)-1-Phenyl-1H-Pyrazole 3-Bromo-1-Methyl-1H-Pyrazole 3-Bromopyrazolo[1,5-A]Pyridine 3-Bromopyrazolo[1,5-A]Pyrimidine 3-Chloro-1-Methyl-1H-Pyrazole 3-Cyclopropyl-1H-Pyrazole 3-Iodo-1-Methyl-1H-Pyrazole 3-Iodo-1H-Pyrazolo[3,4-B]Pyridine 3-Methyl-1-Phenyl-1H-Pyrazole 3-Phenyl-1H-Pyrazol-5-Amine 4,5,6,7-Tetrahydro-1H-Pyrazolo[3,4-C]Pyridine 4,5,6,7-Tetrahydro-1H-Pyrazolo[4,3-C]Pyridine 4,5,6,7-Tetrahydropyrazolo[1,5-A]Pyrazine 4,5,6,7-Tetrahydropyrazolo[1,5-A]Pyridine 4-(1H-Pyrazol-1-Yl)Benzoic Acid 4-(1H-Pyrazol-1-Yl)Piperidine 4-Bromo-1-Methyl-1H-Pyrazole 4-Bromo-1-Phenyl-1H-Pyrazole 4-Bromo-1H-Pyrazolo[3,4-B]Pyridine 4-Bromopyrazolo[1,5-A]Pyridine 4-Chloro-1H-Pyrazole 4-Chloro-1H-Pyrazolo[3,4-B]Pyridine 4-Chloro-1H-Pyrazolo[3,4-D]Pyrimidine 4-Iodo-1H-Pyrazole 4-Methyl-1-Phenyl-1H-Pyrazole 4-Methyl-1H-Pyrazole 4-Nitro-1H-Pyrazole 4-Phenyl-1H-Pyrazole 5,6-Dihydro-4H-Pyrrolo[1,2-B]Pyrazole 5-(Difluoromethyl)-1H-Pyrazole 5-Bromo-1H-Pyrazole 5-Bromo-1H-Pyrazolo[3,4-B]Pyridine 5-Bromo-1H-Pyrazolo[3,4-C]Pyridine 5-Chloro-1H-Pyrazole 5-Chloro-1H-Pyrazolo[3,4-B]Pyridine 5-Chloropyrazolo[1,5-A]Pyrimidine 5-Cyclopropyl-1H-Pyrazole 5-Iodo-1H-Pyrazole 5-Nitro-1H-Pyrazole 5-Nitro-1H-Pyrazolo[3,4-B]Pyridine 5-Phenyl-1H-Pyrazole-3-Carboxylic Acid 6,7-Dihydro-5H-Pyrazolo[5,1-B][1,3]Oxazine 6-Bromopyrazolo[1,5-A]Pyridine 6-Bromopyrazolo[1,5-A]Pyrimidine 6-Chloro-1H-Pyrazolo[3,4-D]Pyrimidine 7-Chloropyrazolo[1,5-A]Pyrimidine Ethyl 1-Phenyl-1H-Pyrazole-3-Carboxylate Ethyl 1-Phenyl-1H-Pyrazole-4-Carboxylate Ethyl 1H-Pyrazole-4-Carboxylate Ethyl Pyrazolo[1,5-A]Pyridine-3-Carboxylate Ethyl Pyrazolo[1,5-A]Pyrimidine-3-Carboxylate Methyl 1H-Pyrazole-4-Carboxylate Methyl 1H-Pyrazolo[3,4-B]Pyridine-5-Carboxylate Methyl Pyrazolo[1,5-A]Pyridine-3-Carboxylate Pyrazolo[1,5-A]Pyrazine Pyrazolo[1,5-A]Pyridine-2-Carboxylic Acid Pyrazolo[1,5-A]Pyridine-3-Carboxylic Acid Pyrazolo[1,5-A]Pyrimidine-3-Carboxylic Acid Tert-Butyl 1H-Pyrazolo[3,4-B]Pyridine-1-Carboxylate Tert-Butyl 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole-1-Carboxylate

By Key Group+−

Amino-Pyrazole-Carboxylate Amino-Pyrazolopyridine Aminopyrazolo Benzylpyrazol-Amide Bipyrazole Bromo-Methyl-Pyrazole Bromo-Pyrazol-Amide Bromo-Pyrazole-Carboxylate Bromo-Pyrazolopyridine Bromo-Pyrazolopyrimidine Bromo-Trifluoromethyl-Pyrazole Bromopyrazolo Chloro-Methyl-Pyrazole Chloro-Pyrazolamide Chloro-Pyrazole Chloro-Pyrazole-Carboxylate Chloro-Pyrazolopyridine Chloro-Pyrazolopyrimidine Chloropyrazolo Dichloropyrazolo Difluoromethyl-Pyrazole Difluoromethyl-Pyrazole-Carboxylate Dihydropyrazolo Dimethyl-Pyrazol-Amide Dimethyl-Pyrazole-Carboxylate Dimethyl-Pyrazole-Carboxylic Acid Dimethylpyrazole Dimethylpyrazolo Dioxaborolan-Pyrazole Ethyl-Pyrazol-Amide Ethylpyrazole Fluoropyrazolo Hydroxy-Pyrazole Hydroxy-Pyrazolopyrimidine Hydroxypyrazolo Iodo-Methyl-Pyrazole Iodo-Pyrazole-Carboxylate Iodopyrazolo Isopropyl-Pyrazol-Amide Methoxy-Pyrazolo-Pyridine Methoxypyrazolo Methy-Pyrazolooxazine Methyl-Hydrox-Ypyrazole Methyl-Nitro-Pyrazole Methyl-Pyrazol-One Methyl-Pyrazole-Carboxylic Acid Methyl-Pyrazole-Carboxylic-Acid Methyl-Pyrazolone Methyl-Pyrazolopyridine Methylpyrazole Methylpyrazolo Nitro-Pyrazole-Carboxylate Phenyl-Pyrazol-Amide Phenyl-Pyrazole-Carboxylate Phenyl-Pyrazolidine Phenylpyrazole Pyrazo-Morpholine Pyrazol-Amine Pyrazol-Boronic Acid Pyrazol-Methanol Pyrazol-One Pyrazol-Piperazine Pyrazol-Pyridine Pyrazole-Carbonitrile Pyrazole-Carboxylate Pyrazole-Carboxylic Acid Pyrazole-Ethanol Pyrazole-Hydrochloride Pyrazole-Methamine Pyrazole-Phenyl-Boronic-Acid Pyrazole-Piperidine Pyrazolo-Pyrimidine Pyrazolooxazine Pyrazolopyrazine Pyrazolopyridin-Ol Pyrazolopyridin-One Pyrazolopyridine Pyrazolopyridine-Carbonitrile Pyrazolopyridine-Carboxylate Pyrazolopyridine-Carboxylic Acid Pyrazolopyridine-Carboxylic-Acid Pyrazolopyridine-Methanol Pyrazolopyrimid-One Pyrazolopyrimidine Pyrazolotriazine Pyridine-Pyrazole Pyrimidine-Pyrazole Pyrrolopyrazole Tetrahydropyran-Pyrazole Tetrahydropyranopyrazole Tetrahydropyrazolo Trifluoromethyl-Phenyl-Pyrazol Trifluoromethyl-Pyrazol-Amide Trifluoromethyl-Pyrazole Trifluoromethyl-Pyrazolone

By Parent Nucleus+−

Aliphatic Heterocycles Aromatic Heterocycles Azetidines Furans Guanidines Imidazoles Indazoles Indoles Other Aliphatic Heterocycles Other Aromatic Heterocycles Oxetanes Piperazines Piperidines Pyrazines Pyridazines Pyridines Pyrimidines Pyrroles Pyrrolidines Quinolines Tetrahydrofurans Tetrahydropyrans Thiophenes

By Functional Group+−

Alcohols Aldehydes Aliphatic Chain Hydrocarbons Aliphatic Cyclic Hydrocarbons Alkenyls Alkyls Alkynyls Amides Amines Aryls Benzyl Bromides Benzyl Chlorides Bromides Carboxylic Acids Chiral Building Blocks Chlorides Difluoromethyls Esters Ethers Fluorinated Building Blocks Hydrazones Iodides Ketones Nitriles Nitroes Oximes Phenols Phosphoruses Sulfamides Sulfides Sulfonates Sulfonic Acids Sulfonyl Chlorides Trifluoromethyls Ureas

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