Home Chemistry Heterocyclic Building Blocks Pyrrolidines 1-Benzylpyrrolidin-2-One
Acid-Catalyzed Hydrolysis: The amide functionality can be hydrolyzed under acidic conditions to form the corresponding carboxylic acid and amine.
Base-Catalyzed Hydrolysis: Under basic conditions, the amide can undergo hydrolysis to yield a carboxylate ion and an amine.
Friedel-Crafts Acylation: The benzyl group can be replaced by an acyl group through Friedel-Crafts acylation reactions.
Nucleophilic Substitution at the Benzyl Carbon: The benzyl carbon is susceptible to nucleophilic substitution reactions.
Aromatic Substitution Reactions: Depending on the conditions and reagents, the aromatic ring can undergo various substitution reactions like halogenation, nitration, sulfonation, etc.
Grignard Reaction: The compound can react with a Grignard reagent to form a tertiary alcohol.
Cyclization Reactions: Given the right conditions, it might participate in cyclization reactions, forming different types of cyclic compounds.
Mannich Reaction: It can participate in Mannich reactions, where an amine, formaldehyde, and a compound with an acidic proton react to form β-amino carbonyl compounds.
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(3R)-5-Oxo-1-[(1R)-1-phenylethyl]pyrrolidine-3-carboxylic acid
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(S)-1-Benzyl-5-oxopyrrolidine-3-carboxylic acid
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(S)-5-Oxo-1-((S)-1-phenylethyl)pyrrolidine-3-carboxylic acid
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4-Amino-1-benzylpyrrolidin-2-one hydrochloride
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4-Amino-1-benzylpyrrolidin-2-one dihydrochloride
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tert-Butyl (1-benzyl-5-oxopyrrolidin-3-yl)carbamate
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Methyl 1-Benzyl-5-oxo-3-pyrrolidinecarboxylate
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(R)-1-Benzyl-5-oxopyrrolidine-3-carboxylic acid
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5-Oxo-1-(1-phenylethyl)pyrrolidine-3-carboxylic acid
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2',3'-Di-O-acetyl-5'-deoxy-5-fluoro-D-cytidine
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