Home Chemistry Heterocyclic Building Blocks Pyridines 2-Chloro-6-Methoxypyridine
Substitution Reactions: The chlorine atom can undergo substitution reactions with various nucleophiles, such as amines or alkoxides, to replace the chlorine atom with the corresponding nucleophile.
Metalation Reactions: The pyridine ring can be metalated at the 2-position or 6-position with strong bases, forming metal complexes that can further react in various ways.
Cross-Coupling Reactions: The halogen atom can participate in cross-coupling reactions, such as Suzuki or Stille couplings, to form biaryl compounds when reacted with suitable coupling partners.
Oxidation/Reduction Reactions: The methoxy group or the pyridine ring can undergo oxidation or reduction reactions under appropriate conditions, leading to the formation of different functional groups.
Functional Group Transformations: The methoxy group can be transformed into other functional groups through various reactions like demethylation, ether cleavage, or substitution reactions.
Heterocycle Formation: The 2-chloro-6-methoxypyridine can participate in heterocycle formation reactions, such as cyclization with suitable reagents to form fused or spiro heterocycles.
Halogenation Reactions: The pyridine ring can undergo further halogenation reactions, depending on the conditions and reagents used.
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Methyl 2-chloro-5-fluoro-6-methoxynicotinate
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2-Chloro-6-methoxypyridine-3-sulfonyl chloride
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(6-Chloro-2-methoxypyridin-3-yl)boronic acid
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2-Chloro-5-fluoro-6-methoxynicotinic acid
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(6-Chloro-2-methoxypyridin-3-yl)methanamine dihydrochloride
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(2-Chloro-6-methoxypyridin-4-yl)methanamine
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(6-Chloro-2-methoxypyridin-3-yl)methanol
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