Home Chemistry Organic Building Blocks Bromides 1-Bromo-2-Fluoro-3-Methylbenzene
These compounds have the same murcko framework: benzene,and at least 3 kinds of functional groups( —Br,—F,—CH3).
Electrophilic Aromatic Substitution (EAS): Bromobenzene can react with electrophiles in substitution reactions, such as nitration, sulfonation, halogenation, and Friedel-Crafts acylation/alkylation.
Cross-Coupling Reactions: Fluorobenzene can be utilized in cross-coupling reactions, such as Suzuki-Miyaura, Negishi, and Stille reactions. These reactions involve coupling a halogenated aromatic compound with an organometallic reagent, resulting in the formation of new carbon-carbon bonds.
Halogenation: Toluene can undergo halogenation reactions with halogens (such as chlorine or bromine) in the presence of a catalyst or under UV light. The hydrogen atoms on the benzene ring can be replaced by halogen atoms, resulting in the formation of mono-, di-, or polyhalogenated derivatives of toluene.
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1-Bromo-2,4,5-trifluoro-3-methylbenzene
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4,6-Dibromo-3-fluoro-2-methyl-benzoic acid methylester
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Methyl 4-bromo-3-fluoro-2-methylbenzoate
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1-Bromo-2-fluoro-3-methyl-5-nitrobenzene
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