Chemistry Organic Building Blocks Benzyl bromides
When benzyl chloride is not sufficiently reactive, benzyl bromide can be employed in organic synthesis to introduce benzyl groups due to its higher reactivity, making it a viable alternative in certain situations.
Benzyl bromide, having the chemical formula C6H5CH2Br, is an organic compound featuring a bromomethyl group substitution on a benzene ring. This colorless liquid possesses lachrymatory properties and serves as a reagent for the introduction of benzyl groups.
Under appropriate conditions for free radical halogenation, toluene can be brominated to synthesize benzyl bromide.
Organic synthesis employs benzyl bromide to incorporate benzyl groups when benzyl chloride, which is less expensive, exhibits inadequate reactivity.
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1-(Bromomethyl)-2-chloro-4-methoxybenzene
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1-(1-Bromoethyl)-3-(trifluoromethyl)benzene
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1-(Bromomethyl)-4-(trifluoromethoxy)benzene
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2-(4-(Bromomethyl)-3-chlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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Methyl 2-(bromomethyl)-3-chlorobenzoate
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4-(Bromomethyl)-1-methoxy-2-nitrobenzene
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2-(2-(Bromomethyl)-5-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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1-(Bromomethyl)-3-(trifluoromethoxy)benzene
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tert-Butyl (2-(bromomethyl)phenyl)carbamate