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Chemical Structure| 18878-89-2 Chemical Structure| 18878-89-2

Structure of 18878-89-2

Chemical Structure| 18878-89-2

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Product Details of [ 18878-89-2 ]

CAS No. :18878-89-2
Formula : C15H13ClO
M.W : 244.72
SMILES Code : COC1=CC=C(/C=C/C2=CC=C(Cl)C=C2)C=C1
English Name :(E)-1-Chloro-4-(4-methoxystyryl)benzene

Safety of [ 18878-89-2 ]

Application In Synthesis of [ 18878-89-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 18878-89-2 ]

[ 18878-89-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 3899-91-0 ]
  • [ 940-62-5 ]
  • [ 18878-89-2 ]
YieldReaction ConditionsOperation in experiment
89% With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; copper dichloride at 100℃; for 12h; 4 Example 4 General procedure: In the reaction flask, p-chlorophenylacrylic acid (1.0 mmol) was added.P-toluenesulfonate aryl ester (1.1 mmol), PdCl 2 (dppf) (0.05 mmol), CuCl 2 (0.2 mmol), KOAc (2.0 mmol) and 2 mL solventDMI (1,3-dimethyl-2-imidazolidinone), stirred, and then heated to 100 ° C for reaction,After 12 hours of reaction, the reaction was completely monitored by TLC, cooled to room temperature and filtered to remove solids.Add 3 mL of water, extract three times with ethyl acetate (3 mL each time), and combine the extracts.Dry over anhydrous sodium sulfate, spin dry solvent,The product was obtained by column separation using a mixed solvent of petroleum ether and ethyl acetate as an eluent.The reaction formula and the reaction result (yield is isolated yield) are as follows:
 

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