Type	HazMat fee for 500 gram (Estimated)
Excepted Quantity	USD 0.00
Limited Quantity	USD 15-60
Inaccessible (Haz class 6.1), Domestic	USD 80+
Inaccessible (Haz class 6.1), International	USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic	USD 100+
Accessible (Haz class 3, 4, 5 or 8), International	USD 200+

CAS No. :	697-72-3
Formula :	C₆H₄N₂OS
M.W :	152.17
SMILES Code :	O=C1C2=C(C=CS2)C=NN1
English Name :	Thieno[2,3-d]pyridazin-7(6H)-one
MDL No. :	MFCD30290616

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Yield	Reaction Conditions	Operation in experiment
12.1 g (36%)	With hydrazine hydrate In methanol	3 Synthesis of Thieno[2,3-d]pyridazin-7(6H)-one (IV-4) The 2,5-disubstituted acid side product was spectrally indicated as an impurity. A sample of the acid-aldehyde 41 (34.0 g, 0.22 mol) was combined with 32.7 g (0.66 mol) of hydrazine monohydrate in methanol and refluxed for 24 hrs. The reaction solution was concentrated in vacuo to a solid which was recrystallized from methanol to yield 12.1 g (36%) of thieno[2,3-d]pyridazin-7(6H)-one (IV-4). The NMR was consistent with the assigned structure.
		36 Thieno[2,3-d]pyridazin-7(6H)-one (xv) Thieno[2,3-d]pyridazin-7(6H)-one (xv) The compound (xv) was prepared from compound (xiv) according to the compound (xii) in example 34. 1H NMR (500 MHz, DMSO) δ 12.93 (s, 1H), 8.44 (s, 1H), 8.19 (d, J = 5.1 Hz, 1H), 7.58 (d, J = 5.1 Hz, 1H). 13C NMR (126 MHz, DMSO) δ 158.19, 139.97, 136.24, 135.83, 134.55, 124.82. HRMS (ESI): cal. mass C6H4N2OS [M+1]+ 153.0117, found [M+1]+ 153.0118, cal. mass C6H4N2OSNa [M+Na]+ 174.9937, found [M+Na]+ 174.9942.

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CAS No.: 697-72-3

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CAS No.: 697-72-3

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Product Details of [ 697-72-3 ]

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[ 697-72-3 ] Synthesis Path-Downstream 1~1

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