Select Region or Location
Americas
  • Argentina
  • Brazil
  • Canada
  • Mexico
  • United States
  • Other Americas
Europe
  • Austria
  • Belgium
  • Bulgaria
  • Croatia/Hrvatska
  • Cyprus
  • Czech Republic
  • Denmark
  • Estonia
  • Finland
  • France
  • Germany
  • Greece
  • Hungary
  • Ireland
  • Italy
  • Latvia
  • Liechtenstein
  • Lithuania
  • Luxembourg
  • Malta
  • Netherlands
  • Norway
  • Poland
  • Portugal
  • Romania
  • Slovak Republic
  • Slovenia
  • Spain
  • Sweden
  • Switzerland
  • Turkey
  • United Kingdom
  • Other Europe
Asia Pacific
  • Australia
  • China
  • India
  • Indonesia
  • Japan
  • Korea, Republic of
  • Malaysia
  • New Zealand
  • Philippines
  • Singapore
  • Thailand
  • Vietnam
  • Other Asia Pacific
Africa And Middle East
  • Egypt
  • Israel
  • Other Africa And Middle East
USD
Home Cart Sign in  
Chemical Structure| 1202681-04-6 Chemical Structure| 1202681-04-6

Structure of Mpeg5-n3
CAS No.: 1202681-04-6

Chemical Structure| 1202681-04-6

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only! Not for Human Use. We Do Not Sell to Patients.

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

DE Stock

US Stock

Asia Stock

Global Stock

In Stock
{[ item.pr_size ]}{[ size_append_text(item.pr_size, proInfo.prAm, 'list') ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

  • {[ item.pr_size ]}
    {[ size_append_text(item.pr_size, proInfo.prAm, 'list') ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 1202681-04-6 ]

CAS No. :1202681-04-6
Formula : C11H23N3O5
M.W : 277.32
SMILES Code : COCCOCCOCCOCCOCCN=[N+]=[N-]
English Name :16-Azido-2,5,8,11,14-pentaoxahexadecane
MDL No. :MFCD31656928

Safety of [ 1202681-04-6 ]

Application In Synthesis of [ 1202681-04-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1202681-04-6 ]

[ 1202681-04-6 ] Synthesis Path-Downstream   1~10

  • 1
  • [ 80755-67-5 ]
  • [ 1202681-04-6 ]
YieldReaction ConditionsOperation in experiment
73% With sodium azide In N,N-dimethyl-formamide at 80℃; for 11.5h; Inert atmosphere;
57% With sodium azide In N,N-dimethyl-formamide at 80℃; for 11.5h; 6 [Example 6: Synthesis of compound of the present invention 5] Compounds of the present invention having a PEG chain were synthesized in the same manner as in Example 5. Compound 28 (2-(2-(2-methoxyethoxy)ethoxy)ethyl 4-methylbenzenesulfonate) was synthesized from Compound 27 as previously reported ()). Compound 29 (2,5,8,11,14-pentaoxahexadecan-16-ol) was synthesized from Compound 28 as previously reported ()). Compound 30 (2,5,8,11,14-pentaoxahexadecan-16-yl 4-methylbenzenesulfonate) was synthesized from Compound 29 as previously reported ()). To a stirring solution of Compound 30 (813 mg, 2 mmol) in DMF (2 mL), NaN3 (308 mg, 1.61 mmol) was added at room temperature. The reaction mixture was stirred at 80°C for 11.5 hours, and then concentrated under reduced pressure. A precipitate was filtered to obtain Compound 31 (16-azido-2,5,8,11,14-pentaoxahexadecane) (355 mg, yield 57%) as a solid. 1H-NMR (400 MHz, CDCl3) δ 3.37-3.40 (m, 5H), 3.53-3.56 (m, 2H), 3.63-3.68 (m, 16H; 13C NMR (125 MHz, CDCl3) δ50.7, 59.0, 70.0, 70.6(7C), 71.9; HRMS (ESI), C11H23N3NaO5[M+H]+m/z calculated: 300.1530, found: 300.1526.
57% With sodium azide In N,N-dimethyl-formamide at 80℃; for 11.5h; 6 [Example 6: Synthesis of compound of the present invention 5] Compounds of the present invention having a PEG chain were synthesized in the same manner as in Example 5. Compound 28 (2-(2-(2-methoxyethoxy)ethoxy)ethyl 4-methylbenzenesulfonate) was synthesized from Compound 27 as previously reported ()). Compound 29 (2,5,8,11,14-pentaoxahexadecan-16-ol) was synthesized from Compound 28 as previously reported ()). Compound 30 (2,5,8,11,14-pentaoxahexadecan-16-yl 4-methylbenzenesulfonate) was synthesized from Compound 29 as previously reported ()). To a stirring solution of Compound 30 (813 mg, 2 mmol) in DMF (2 mL), NaN3 (308 mg, 1.61 mmol) was added at room temperature. The reaction mixture was stirred at 80°C for 11.5 hours, and then concentrated under reduced pressure. A precipitate was filtered to obtain Compound 31 (16-azido-2,5,8,11,14-pentaoxahexadecane) (355 mg, yield 57%) as a solid. 1H-NMR (400 MHz, CDCl3) δ 3.37-3.40 (m, 5H), 3.53-3.56 (m, 2H), 3.63-3.68 (m, 16H; 13C NMR (125 MHz, CDCl3) δ50.7, 59.0, 70.0, 70.6(7C), 71.9; HRMS (ESI), C11H23N3NaO5[M+H]+m/z calculated: 300.1530, found: 300.1526.
With sodium azide In N,N-dimethyl-formamide at 50℃; for 12h;
57 % With sodium azide In N,N-dimethyl-formamide at 80℃; 6 [Example 6: Synthesis of compound of the present invention 5] Compounds of the present invention having a PEG chain were synthesized in the same manner as in Example 5. Compound 28 (2-(2-(2-methoxyethoxy)ethoxy)ethyl 4-methylbenzenesulfonate) was synthesized from Compound 27 as previously reported ()). Compound 29 (2,5,8,11,14-pentaoxahexadecan-16-ol) was synthesized from Compound 28 as previously reported ()). Compound 30 (2,5,8,11,14-pentaoxahexadecan-16-yl 4-methylbenzenesulfonate) was synthesized from Compound 29 as previously reported ()). To a stirring solution of Compound 30 (813 mg, 2 mmol) in DMF (2 mL), NaN3 (308 mg, 1.61 mmol) was added at room temperature. The reaction mixture was stirred at 80°C for 11.5 hours, and then concentrated under reduced pressure. A precipitate was filtered to obtain Compound 31 (16-azido-2,5,8,11,14-pentaoxahexadecane) (355 mg, yield 57%) as a solid. 1H-NMR (400 MHz, CDCl3) δ 3.37-3.40 (m, 5H), 3.53-3.56 (m, 2H), 3.63-3.68 (m, 16H; 13C NMR (125 MHz, CDCl3) δ50.7, 59.0, 70.0, 70.6(7C), 71.9; HRMS (ESI), C11H23N3NaO5[M+H]+m/z calculated: 300.1530, found: 300.1526.

  • 3
  • [ 23778-52-1 ]
  • [ 1202681-04-6 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: pyridine / 0 °C 2: sodium azide / dimethylformamide / 12 h / 50 °C
Multi-step reaction with 2 steps 1: triethylamine; dmap / dichloromethane / 5 h / 20 °C / Inert atmosphere 2: sodium azide / N,N-dimethyl-formamide / 11.5 h / 80 °C / Inert atmosphere
  • 4
  • [ 1202681-04-6 ]
  • [ 155726-45-7 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: 1.) PPh3, 2.) H2O / 1.) THF, RT, 12 h, 2.) RT, 12 h 2: 20 mM KH2PO4 / acetone / 2 h / Ambient temperature
  • 5
  • [ 112-35-6 ]
  • [ 1202681-04-6 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 4 steps 1: triethylamine; dmap / dichloromethane / 8 h / 20 °C / Inert atmosphere 2: sodium hydride / tetrahydrofuran / 15 h / 80 °C / Inert atmosphere 3: triethylamine; dmap / dichloromethane / 5 h / 20 °C / Inert atmosphere 4: sodium azide / N,N-dimethyl-formamide / 11.5 h / 80 °C / Inert atmosphere
  • 6
  • [ 62921-74-8 ]
  • [ 1202681-04-6 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 3 steps 1: sodium hydride / tetrahydrofuran / 15 h / 80 °C / Inert atmosphere 2: triethylamine; dmap / dichloromethane / 5 h / 20 °C / Inert atmosphere 3: sodium azide / N,N-dimethyl-formamide / 11.5 h / 80 °C / Inert atmosphere
  • 7
  • [ 1202681-04-6 ]
  • [ 2641814-73-3 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: hydrogen; palladium on activated charcoal / methanol / 2 h / 20 °C 2: triethylamine / dichloromethane / 15.5 h / 20 °C / Inert atmosphere
  • 8
  • [ 1202681-04-6 ]
  • [ 2641814-74-4 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 3 steps 1: hydrogen; palladium on activated charcoal / methanol / 2 h / 20 °C 2: triethylamine / dichloromethane / 15.5 h / 20 °C / Inert atmosphere 3: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane; 1,2-dimethoxyethane / 2 h / 20 °C / Inert atmosphere
  • 9
  • [ 1202681-04-6 ]
  • [ 2758032-41-4 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 4 steps 1.1: hydrogen; palladium on activated charcoal / methanol / 2 h / 20 °C 2.1: triethylamine / dichloromethane / 15.5 h / 20 °C / Inert atmosphere 3.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane; 1,2-dimethoxyethane / 2 h / 20 °C / Inert atmosphere 4.1: sodium carbonate decahydrate / water; 1,4-dioxane / 1.5 h / 20 °C / Inert atmosphere 4.2: 12 h / 20 °C / Inert atmosphere
  • 10
  • [ 1202681-04-6 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 5 steps 1.1: hydrogen; palladium on activated charcoal / methanol / 2 h / 20 °C 2.1: triethylamine / dichloromethane / 15.5 h / 20 °C / Inert atmosphere 3.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane; 1,2-dimethoxyethane / 2 h / 20 °C / Inert atmosphere 4.1: sodium carbonate decahydrate / water; 1,4-dioxane / 1.5 h / 20 °C / Inert atmosphere 4.2: 12 h / 20 °C / Inert atmosphere 5.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 18 h / 20 °C / Inert atmosphere
 

Historical Records

Categories