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Chemical Structure| 2064292-12-0 Chemical Structure| 2064292-12-0

Structure of A1874
CAS No.: 2064292-12-0

Chemical Structure| 2064292-12-0

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A1874 is a nutlin-based PROTAC targeting on BRD4, consist of a BRD4-ligand JQ1 linked to a MDM2 E3 ligase ligand RG7388.

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Product Details of A1874

CAS No. :2064292-12-0
Formula : C58H62Cl3F2N9O7S
M.W : 1173.59
SMILES Code : O=C(NCCOCCOCCOCCNC(C1=CC=C(NC([C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(C3=CC=C(Cl)C=C3F)[C@H]2C4=CC=CC(Cl)=C4F)=O)C(OC)=C1)=O)C[C@H]5C6=NN=C(C)N6C7=C(C(C)=C(C)S7)C(C8=CC=C(Cl)C=C8)=N5
MDL No. :MFCD31813733

Safety of A1874

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Related Pathways of A1874

epigenetics

Isoform Comparison

Biological Activity

Target
  • BET

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

0.85mL

0.17mL

0.09mL

4.26mL

0.85mL

0.43mL

8.52mL

1.70mL

0.85mL

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