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Chemical Structure| 2105904-82-1 Chemical Structure| 2105904-82-1

Structure of AB-680
CAS No.: 2105904-82-1

Chemical Structure| 2105904-82-1

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AB680 is a potent human CD73 inhibitor with Ki value of 5pM. It is the first small-mol. CD73 inhibitor to enter clin. development.

Synonyms: AB-680

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Product Details of AB-680

CAS No. :2105904-82-1
Formula : C20H24ClFN4O9P2
M.W : 580.82
SMILES Code : [H][C@@]1([C@H](O)[C@H](O)[C@@H](COP(O)(CP(O)(O)=O)=O)O1)N2N=CC3=C(C=C(Cl)N=C32)N[C@@H](C)C4=C(F)C=CC=C4
Synonyms :
AB-680
MDL No. :MFCD32062822

Safety of AB-680

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.72mL

0.34mL

0.17mL

8.61mL

1.72mL

0.86mL

17.22mL

3.44mL

1.72mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

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