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Chemical Structure| 948044-25-5 Chemical Structure| 948044-25-5

Structure of ACA-28
CAS No.: 948044-25-5

Chemical Structure| 948044-25-5

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ACA-28 is a potent ERK MAPK signaling modulator that selectively inhibits cancer cell growth and induces apoptosis. It activates the nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway by inducing reactive oxygen species (ROS) production and can be used for cancer research such as melanoma.

4.5 *For Research Use Only! Not for Human Use. We Do Not Sell to Patients.

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Product Details of ACA-28

CAS No. :948044-25-5
Formula : C17H16O6
M.W : 316.31
SMILES Code : O=C(OC1=CC=C(C(OC(OC)=O)C2=CC=CC=C2)C=C1)OC
English Name :4-(((Methoxycarbonyl)oxy)(phenyl)methyl)phenyl methyl carbonate
MDL No. :N/A

Safety of ACA-28

Related Pathways of ACA-28

MAPK

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.16mL

0.63mL

0.32mL

15.81mL

3.16mL

1.58mL

31.61mL

6.32mL

3.16mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2
 

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