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Chemical Structure| 18642-44-9 Chemical Structure| 18642-44-9

Structure of Actein
CAS No.: 18642-44-9

Chemical Structure| 18642-44-9

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Actein, a natural product isolated and purified from the roots of Cimicifuga racemosa with stimulatory effect on osteoblastic bone formation and potential activity against osteoporosis, has been shown to inhibit the proliferation of human breast cancer cells, by altering the activity of the ER IP3 receptor and Na,K-ATPase, inducing calcium release and modulating the NF-κB and MEK pathways, and reduces free fatty acid and cholesterol content in the liver by 0.6-fold at 24 h and inhibites the growth of human HepG2 liver cancer cells.

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Product Details of Actein

CAS No. :18642-44-9
Formula : C37H56O11
M.W : 676.83
SMILES Code : C[C@]12[C@]3([C@]4([C@]5(C4)[C@@]([H])(CC3)C([C@H](CC5)O[C@]6([C@H](O)[C@@H](O)[C@@H](CO6)O)[H])(C)C)C[C@H]([C@]1(C)[C@@]7([C@]([H])(C2)O[C@@]8(C[C@H]7C)[C@H]9[C@](C)(O9)[C@H](O8)O)[H])OC(C)=O)[H]
MDL No. :MFCD25371991

Safety of Actein

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Related Pathways of Actein

MAPK
PI3K-AKT
TLR

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.48mL

0.30mL

0.15mL

7.39mL

1.48mL

0.74mL

14.77mL

2.95mL

1.48mL

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