Structure of Arundic Acid
CAS No.: 185517-21-9
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The BI-3802 was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.
Arundic acid (ONO-2506) is an astrocyte modulator that inhibits the synthesis of S-100β, regulating astrocyte activation to delay the expansion of cerebral infarcts. Arundic acid has potential for stroke and Alzheimer's disease research.
Synonyms: ONO-2506; (R)-2-Propyloctanoic acid; Proglia
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CAS No. : | 185517-21-9 |
Formula : | C11H22O2 |
M.W : | 186.29 |
SMILES Code : | CCCCCC[C@@H](CCC)C(O)=O |
Synonyms : |
ONO-2506; (R)-2-Propyloctanoic acid; Proglia
|
MDL No. : | MFCD08458423 |
InChI Key : | YCYMCMYLORLIJX-SNVBAGLBSA-N |
Pubchem ID : | 208925 |
GHS Pictogram: |
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Signal Word: | Warning |
Hazard Statements: | H302-H315-H319-H335 |
Precautionary Statements: | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
Clinical Trial:
NCT Number | Conditions | Phases | Recruitment | Completion Date | Locations |
NCT00694941 | Amyotrophic Lateral Sclerosis ... More >>(ALS) Less << | PHASE2 | COMPLETED | - | Prof. Maloteaux, UCL Saint-Luc... More >>, Brussels, Belgium|Prof. Wim Robberecht, UZ Leuven, Leuven, Belgium|Prof. Alain Destee, Hopital Roger Salengro - Clinique Neurologique, Neurologie A, Lille Cedex, France|Prof. Philippe Couratier, Hopital Duruytren, Limoges Cedex, France|Prof. Jan Pouget, Hopital de la Timone, Marseille, France|Prof. William Camu, Hopital de Chauliac, Montpellier cedex 5, France|Prof. Claude Desnuelle, Hopital 1-Archet 1, Nice cedex 3, France|Prof. Vincent Meininger, Hopital LaPitie Salpetriere, Paris, France|Dr. Thomas Meyer, Charite Campus Virchow, ALS Ambulanz, Berlin, Germany|Prof. Torsten Grehl, Neurologische Ambulanz Universitatsklinik Bergmannsheil, Bochum, Germany|Professor Dieter Heuss, Poliklinik der Universitat Erlangen-Nurnberg, Neurologische Klinik, Erlangen, Germany|Prof. Stephan Zierz, Martin Luther Universitat Halle-Wittenberg, Klinikum der Medizinischen Fakultat, Universitatsklinik und Poliklinik fur Neurologie, Halle, Germany|Prof. Reinhard Dengler, Medizinische Hochschule Hannover, Neurologische Klinik, Hannover, Germany|Prof Gian Domenico Borasio, Interdisziplinares Zentrum fur Palliativmedizin, Munchen, Germany|Prof. Albert Ludolph, Klinik und Poliklinikfur Neurologie der Universitat Ulm-Univeritatsklinikum Ulm, Ulm, Germany|Dr. Berthold Schrank, Deutsche Klinik fur Diagnostik, Fachbereich Neurologie, Wiesbarden, Germany|Prof. Vincenzo Silani, Dipartimento di Neurologia e Laboratorio di Neuroscienze - Universita di Milano - IRCCS - Istituto Auxologico Italiano, Milano, Italy|Dr. Gabriele Mora, Divisione di Neuroriabilitazione II - Fondazione Salvatore Maugeri - IRCCS, Pavia, Italy|Prof. Adriano Chio, Dipartimento di Neuroscienze - Divisione di Neurologia II - Azienda Ospedaliera S. Giovanni Battista - Molinette, Torino, Italy|Prof Marianne de Visser, Academic Medical Centre (AMC) Amsterdam - Dept of Neurology, Amsterdam, Netherlands|Prof. Leonard H Van Den Berg, University Medical Center Utrecht, Utrecht, Netherlands|Dr. Markus Weber, Kantonsspital St. Gallen, Muskelzentrum/ALS Clinic, St. Gallen, Switzerland|Prof. Nigel Leigh, Academic Neuroscience Centre, London, United Kingdom|Prof. Douglas Mitchell, Royal Preston Hospital, Preston, United Kingdom|Dr. Chris McDermott, Royal Hallamshire Hospital, Sheffield, United Kingdom Less << |
NCT00046761 | Cerebrovascular Accident | PHASE2|PHASE3 | TERMINATED | - | Brookwood Medical Center, Birm... More >>ingham, Alabama, 35209, United States|University of Alabama, Birmingham, Alabama, 35294, United States|Alta Bates Hospital/ Summit Medical Center, Berkeley, California, 94705, United States|Grossmont Hospital, La Mesa, California, 91942, United States|Loma Linda University Medical Center, Loma Linda, California, 92354, United States|UCLA Medical Center, Los Angeles, California, 90024, United States|Stanford Stroke Center, Palo Alto, California, 94304, United States|Mercy Medical Center, Redding, California, 96001, United States|Redding Medical Center, Redding, California, 96001, United States|UC Davis Medical Center, Sacramento, California, 95817, United States|Good Samaritan Hospital, San Jose, California, 95124, United States|Bridgeport Hospital, Bridgeport, Connecticut, 06610, United States|The Stroke Center at Hartford Hospital, Hartford, Connecticut, 06106, United States|Yale - New Haven Hospital, New Haven, Connecticut, 06520, United States|Morton Plant Hospital, Clearwater, Florida, 33756, United States|North Broward Medical Center, Ft. Lauderdale, Florida, 33308, United States|Alachua General Hospital, Gainsville, Florida, 32605, United States|Aventura Hospital and Medical Center, Hollywood, Florida, 33021, United States|Neurology Associates, PA, Maitland, Florida, 32751, United States|Baptist Hospital of Miami, Miami, Florida, 33156, United States|Ocala Regional Medical Center, Ocala, Florida, 34471, United States|Munroe Regional Medical Center, Ocala, Florida, 34478, United States|BonSecours - St. Joseph's Hospital, Port Charlotte, Florida, 33952, United States|Charlotte Regional Medical Center, Port Charlotte, Florida, 33952, United States|Fawcett Memorial Hospital, Port Charlotte, Florida, 33952, United States|Bayfront Medical Center, St. Petersburg, Florida, 33701, United States|Palms of Pasadina Hospital, St. Petersburg, Florida, 33707, United States|St. Joseph Hospital, Tampa, Florida, 33606, United States|Tampa General Hospital, Tampa, Florida, 33606, United States|Memorial Hospital of Tampa, Tampa, Florida, 33608, United States|Cleveland Clinic Florida, Weston, Florida, 33331, United States|St. Francis Hospital, Columbus, Georgia, 31901, United States|DeKalb Medical Center, Decatur, Georgia, 30033, United States|Gwinnett Medical Center, Decatur, Georgia, 30033, United States|Joan Glancy Memorial Hospital, Decatur, Georgia, 30034, United States|Queen's Medical Center, Honolulu, Hawaii, 96813, United States|MacNeal Hospital, Berwyn, Illinois, 60402, United States|BroMenn Regional Medical Center, Bloomington, Illinois, 61704, United States|OSF St. Joseph Medical Center, Bloomington, Illinois, 61704, United States|Alexian Brothers Hospital, Elk Grove Village, Illinois, 60007, United States|Advocate Christ Hospital & Medical Center, Oak Lawn, Illinois, 60453, United States|St. John's Hospital, Springfield, Illinois, 62702, United States|Memorial Medical Center, Springfield, Illinois, 62781, United States|Central DuPage Hospital, Warrenville, Illinois, 60555, United States|Elkhart General Hospital, Elkhart, Indiana, 46540, United States|Lutheran Hospital of Indiana, Fort Wayne, Indiana, 46804, United States|Parkview Hospital, Fort Wayne, Indiana, 46805, United States|Mercy Hospital Medical Center, Des Moines, Iowa, 50314, United States|University of Kansas Medical Center, Kansas City, Kansas, 66160, United States|Lexington Clinic, Lexington, Kentucky, 40504, United States|Chandler Medical Center /Univ of Kentucky, Lexington, Kentucky, 40536, United States|University of Louisville Hospital, Louisville, Kentucky, 40202, United States|Ochsner Clinic Foundation, New Orleans, Louisiana, 70121, United States|LSU Health Sciences Center, Shreveport, Louisiana, 71130, United States|Sinai Hospital of Baltimore, Baltimore, Maryland, 21215, United States|University of Massachusetts Medical Center, Worcester, Massachusetts, 01655, United States|Detroit Receiving Hospital/ Wayne State Univ, Detroit, Michigan, 48201, United States|Borgess Research Institute, Kalamazoo, Michigan, 49048, United States|William Beaumont Hospital, Royal Oak, Michigan, 48073, United States|St. Cloud Hospital, St. Cloud, Minnesota, 56303, United States|North Mississippi Medical Center, Tupelo, Mississippi, 38801, United States|St. John's Clinic - Smith-Glynn-Callaway, Springfield, Missouri, 65804, United States|Benefits Healthcare/ Advanced Neurology Specialists, Great Falls, Montana, 59405, United States|Creighton University Medical Center, Omaha, Nebraska, 68131, United States|Washoe Medical Center, Reno, Nevada, 89502, United States|Cooper Hospital /University Medical Center, Camden, New Jersey, 08103, United States|JFK Medical Center, Edison, New Jersey, 08818, United States|Englewood Hospital and Medical Center, Englewood, New Jersey, 07631, United States|Virtua Memorial Hospital, Medford, New Jersey, 08055, United States|Robert Wood Johnson Hospital, New Brunswick, New Jersey, 08901, United States|Muhlenberg Hospital, Plainfield, New Jersey, 07061, United States|Valley Hospital, Ridgewood, New Jersey, 08629, United States|Overlook Hospital, Summit, New Jersey, 07091, United States|Community Medical Center, Toms River, New Jersey, 08755, United States|St. Francis Medical Center, Trenton, New Jersey, 08629, United States|St. Peter's Hospital, Albany, New York, 12208, United States|Buffalo General Hospital, Buffalo, New York, 14203, United States|Millard Fillmore Hospital, Buffalo, New York, 14209, United States|Wilson Memorial Regional Medical Center, Johnson City, New York, 13790, United States|North Shore University Hospital, Manhasset, New York, 11030, United States|Winthrop University Hospital, Mineola, New York, 11501, United States|Mount Vernon Hospital, Mount Vernon, New York, 10550, United States|Long Island Jewish Medical Center, New Hyde Park, New York, 11040, United States|Mt. Sinai Hospital, New York, New York, 10029, United States|Rochester General Hospital, Rochester, New York, 14621, United States|Strong Memorial Hospital, Rochester, New York, 14642, United States|Ellis Hospital Stroke Center B421, Schenectady, New York, 12308, United States|SUNY Stony Brook University Hospital, Stony Brook, New York, 11794, United States|University of North Carolina Hospital, Chapel Hill, North Carolina, 27599, United States|Rowan Regional Medical Center, Salisbury, North Carolina, 28144, United States|Forsyth Medical Center, Winston-Salem, North Carolina, 27103, United States|Akron General Medical Center, Akron, Ohio, 44307, United States|University Hospitals of Cleveland, Cleveland, Ohio, 44106, United States|Metrohealth Medical Center, Cleveland, Ohio, 44109, United States|Kettering Medical Center -Wallace Kettering Neuroscience Inst., Kettering, Ohio, 45429, United States|Medical College of Ohio Hospital, Toledo, Ohio, 43614, United States|St. Elizabeth's Health Center, Youngstown, Ohio, 44501, United States|Rogue Valley Medical Center, Medford, Oregon, 97504, United States|Oregon Health and Science University - Oregon Stroke Center, Portland, Oregon, 97201, United States|Providence Portland Medical Center, Portland, Oregon, 97213, United States|Providence St. Vincent's Hospital, Portland, Oregon, 97225, United States|Lehigh Valley Hospital, Allentown, Pennsylvania, 18103, United States|Westmoreland Regional Hospital, Greensburg, Pennsylvania, 15601, United States|University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, 19104, United States|Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, 19107, United States|University of Pittsburg Medical Center, Pittsburg, Pennsylvania, 15213, United States|Crozer Chester Medical Center, Upland, Pennsylvania, 19013, United States|York Hospital, York, Pennsylvania, 17402, United States|Miriam Hospital, Providence, Rhode Island, 02906, United States|Greenville Hospital, Greenville, South Carolina, 29615, United States|Erlanger Hospital, Chattanooga, Tennessee, 37403, United States|Regional Medical Center at Memphis, Memphis, Tennessee, 38103, United States|Vanderbilt University Medical Center, Nashville, Tennessee, 37232, United States|Baylor University Medical Center, Dallas, Texas, 75214, United States|University of Texas; Southwestern Medical Center at Dallas, Dallas, Texas, 75390, United States|Methodist Hospital /Baylor College of Medicine, Houston, Texas, 77030, United States|The Methodist Hospital, Houston, Texas, 77030, United States|University Hospital /Univ of Texas Health Science Center, San Antonio, Texas, 78229, United States|University of Utah Medical Center, Salt Lake City, Utah, 84132, United States|The Innovative Clincal Research Center, Alexandria, Virginia, 22304, United States|Virginia Commonwealth University /Medical College of VA, Richmond, Virginia, 23219, United States|Henrico Doctors Hospital, Richmond, Virginia, 23226, United States|Memorial Regional Medical Center, Richmond, Virginia, 23226, United States|St. Mary's Hospital, Richmond, Virginia, 23226, United States|Harborview Medical Center, Seattle, Washington, 98104, United States|Charleston Area Medical Center, Charleston, West Virginia, 25301, United States|University of Wisconsin Hospitals and Clinics, Madison, Wisconsin, 53792, United States|St. Joseph's Hospital/ Marshfield Clinic, Marshfield, Wisconsin, 54449, United States|St. Luke's Medical Center, Milwaukee, Wisconsin, 53215, United States|Theda Clark Medical Center, Neenah, Wisconsin, 54956, United States|Foothills Medical Center /University of Calgary, Calgary, Alberta, T2N 2T9, Canada|University of Alberta Hospital /Mackenzie Center, Edmonton, Alberta, T6G 2B7, Canada|Lethbridge Regional Hospital, Lethbridge, Alberta, T1O 1W5, Canada|Royal Inland Hospital, Kamloops, British Columbia, V2C 2T1, Canada|Kelowna General Hospital, Kelowna, British Columbia, V1Y 1T2, Canada|St Paul's Hospital, Vancouver, British Columbia, U6Z 2A5, Canada|Vancouver General Hospital, Vancouver, British Columbia, V5Z 1M9, Canada|Royal Jubilee Hospital, Victoria, British Columbia, V8R 4R2, Canada|Kingston General Hospital, Kingston, Ontario, K7L 2V7, Canada|London Health Sciences Centre, London, Ontario, N6A 5A5, Canada|Trillium Health Centre, Mississauga, Ontario, L5B 4A2, Canada|York Central Hospital, Richmond Hill, Ontario, L4C 9M7, Canada|Complexe Hospitalier de La Sagamie, Chicoutimi, Quebec, G7H 5H6, Canada|Centre Hospitalier des Vallees de l'Outaouais, Gatineau, Quebec, J8Y 1W7, Canada|Hotel-Dieu de Levis, Levis, Quebec, G6V 3Z1, Canada|Hospital Notre Dame du Chum, Montreal, Quebec, H2L 4M1, Canada|Hotel-Dieu de St-Jerome, Saint-Jerome, Quebec, J7Z5T3, Canada|Royal University Hospital, Saskatoon, Saskatchewan, S7N 0W8, Canada Less << |
NCT00083421 | Alzheimer's Disease | PHASE2 | COMPLETED | 2025-07-07 | Kirkland Clinic, Birmingham, A... More >>labama, 35233, United States|Alzheimers Disease Research Center, Birmingham, Alabama, 35294, United States|Pivotal Research Center, Mesa, Arizona, 85210, United States|HOPE Research Institute, Phoenix, Arizona, 85032, United States|Sun Health Research Institute, Sun City, Arizona, 85351, United States|University of Arizona, Tucson, Arizona, 85724, United States|Margolin Brain Institute, Fresno, California, 93720, United States|UCI Medical Center Neuropsychiatric Center, Orange, California, 92868, United States|Pacific Neuroscience Medical Group, Oxnard, California, 93030, United States|The Southwest Institute for Clinical Research, Inc, Rancho Mirage, California, 92270, United States|Hamid Rabiee, MD, Redding, California, 96001, United States|Alzheimers Disease Research Center, Univ of CA, San Diego, San Diego, California, 92037, United States|Pacific Research Network, San Diego, California, 92103, United States|San Francisco Clinical Research Center, San Francisco, California, 94109, United States|Apex Research Institute, Santa Ana, California, 92705, United States|Pacific Neuroscience Medical Group, Santa Barbara, California, 93101, United States|Neurological Research Institute, Santa Monica, California, 90404, United States|Radiant Research, Denver, Colorado, 80212, United States|Research Center for Clinical Studies, Inc., Darien, Connecticut, 06820, United States|GAP Clinical Care & Research Center, Hamden, Connecticut, 06518, United States|Baumel-Eisner Neuromedical Institute, Boca Raton, Florida, 33431, United States|Neurologic Consultants, Ft. Lauderdale, Florida, 33308, United States|Baumel-Eisner Neuromedical Institute, Ft. Lauderdale, Florida, 33321, United States|Gainsville Open MRI, Gainsville, Florida, 32607, United States|Berma Research Group, Hialeah, Florida, 33016, United States|Baumel-Eisner Neuromedical Institute, Miami Beach, Florida, 33154, United States|Miami Jewish and Hospital for the Aged, Miami, Florida, 33137, United States|Palm Beach Neurological Center, Palm Beach Gardens, Florida, 33410, United States|Research Site, Port Charlotte, Florida, 33952, United States|Suncoast Neuroscience Associates, St. Petersburg, Florida, 33701, United States|Meridien Research, St. Petersburg, Florida, 33709, United States|Axiom Clinical Research of Florida, Tampa, Florida, 33609, United States|Johnnie B. Byrd Sr. Alzheimer's Center and Research Institute, Tampa, Florida, 33647, United States|Premiere Research Institute, West Palm Beach, Florida, 33407, United States|DeKalb Neurology Associates, Atlanta, Georgia, 30033, United States|Emory University, Atlanta, Georgia, 30329, United States|Mercer University, Atlanta, Georgia, 30341, United States|Rush Alzheimers Disease Center, Chicago, Illinois, 60612, United States|University of Illinois at Chicago, Chicago, Illinois, 60612, United States|Radiant Research, Hoffman Estates, Illinois, 60194, United States|Southern Illinois School of Medicine, Springfield, Illinois, 62702, United States|Fort Wayne Neurological Center, Fort Wayne, Indiana, 46805, United States|Center for Alzheimers Disease and Related Disorders, Indianapolis, Indiana, 46202, United States|Agewell, Indianapolis, Indiana, 46260, United States|Louisiana State University Health Sciences Cntr - Dept of Psychiatry, New Orleans, Louisiana, 70112, United States|J. Gary Booker, M.D., APMC, Shreveport, Louisiana, 71101, United States|St. Louis University Medical Center, St. Louis, Missouri, 63104, United States|University of Nevada, Las Vegas, Nevada, 89102, United States|Meridian Institue for Aging, Manchester, New Jersey, 08759, United States|Mid Atlantic Geriatric Association, Ocean Township, New Jersey, 07712, United States|St. Francis Medical Center, Trenton, New Jersey, 08629, United States|Upstate Clinical Reserach, LLC, Albany, New York, 12205, United States|Upstate Neurology Consults, LLP, Albany, New York, 12205, United States|Neurological Associates of Albany, Albany, New York, 12208, United States|Neurobehavioral Research Inc., Lawrence, New York, 11559, United States|Eastside Comprehensive Medical Services, New York, New York, 10021, United States|Global Reserach & Consulting, Olean, New York, 14760, United States|Monroe Community Hospital, Rochester, New York, 14620, United States|Behavioral Medical Research, Staten Island, New York, 10305, United States|Duke University Medical Center, Durham, North Carolina, 27710, United States|Metrohealth Medical Center, Cleveland, Ohio, 44109, United States|Ohio State University Hospital, Columbus, Ohio, 43210, United States|Infinity Research Group, LLC, Oklahoma City, Oklahoma, 73103, United States|Clinical Pharmaceutical Trials, Tulsa, Oklahoma, 74104, United States|Medford Neurological and Spine Clinic, Medford, Oregon, 97504, United States|Summit Research Network, Portland, Oregon, 97223, United States|Oregon Health and Science University, Portland, Oregon, 97239, United States|Westmoreland Neurology Associates, Inc., Greensburg, Pennsylvania, 15601, United States|University of PA, Section Geriatric Psychiatry, Philadelphia, Pennsylvania, 19104, United States|Alzheimer Disease Research Center, Univ of Pittsburg, Pittsburg, Pennsylvania, 15213, United States|Miriam Hospital, Providence, Rhode Island, 02906, United States|Medical University of South Carolina, Alzheimers Research and Clinical Programs, North Charleston, South Carolina, 29406, United States|Claghorn Lesem Research Clinic, Bellaire, Texas, 77401, United States|Memory Research Unit, Univ of Texas Southwest Med Ctr at Dallas, Dallas, Texas, 75390, United States|Radiant Research San Antonio, San Antonio, Texas, 78229, United States|Neurological Consultants, PC, Bennington, Vermont, 05201, United States|Innovative Clinical Research Center, Alexandria, Virginia, 22304, United States|Medical College of Wisconsin, Department of Neurology, Milwaukee, Wisconsin, 53226, United States|Independent Psychiatric Consultants, Waukesha, Wisconsin, 53188, United States|Inova Health Research, Inc., Kelowna, British Columbia, V1W 4V5, Canada|University of British Columbia Hospital, Vancouver, British Columbia, V6T 2B5, Canada|Davidson Memory Clinic, Moncton, New Brunswick, E1C 4B7, Canada|Parkwood Hospital, Geriatric Medicine, London, Ontario, N6C 5J1, Canada|SCO Health Centre, Ottawa, Ontario, KIN 5C8, Canada|Toronto Memory Program, Toronto, Ontario, M3B 2W7, Canada|Hopital Maisonneuve-Rosemont, Montreal, Quebec, H1T 2M4, Canada|Pasqua Hospital, Regina, Saskatchewan, S4T 1A5, Canada Less << |
NCT00212693 | Parkinson's Disease | PHASE2 | COMPLETED | - | - |
Tags: Arundic Acid | ONO-2506 | Chiral Building Blocks | Carboxylic Acids | Aliphatic Chain Hydrocarbons | S100β | Asymmetric Synthesis | Organic Building Blocks | Neuronal Signaling | 185517-21-9
Precautionary Statements-General | |
Code | Phrase |
P101 | If medical advice is needed,have product container or label at hand. |
P102 | Keep out of reach of children. |
P103 | Read label before use |
Prevention | |
Code | Phrase |
P201 | Obtain special instructions before use. |
P202 | Do not handle until all safety precautions have been read and understood. |
P210 | Keep away from heat/sparks/open flames/hot surfaces. - No smoking. |
P211 | Do not spray on an open flame or other ignition source. |
P220 | Keep/Store away from clothing/combustible materials. |
P221 | Take any precaution to avoid mixing with combustibles |
P222 | Do not allow contact with air. |
P223 | Keep away from any possible contact with water, because of violent reaction and possible flash fire. |
P230 | Keep wetted |
P231 | Handle under inert gas. |
P232 | Protect from moisture. |
P233 | Keep container tightly closed. |
P234 | Keep only in original container. |
P235 | Keep cool |
P240 | Ground/bond container and receiving equipment. |
P241 | Use explosion-proof electrical/ventilating/lighting/equipment. |
P242 | Use only non-sparking tools. |
P243 | Take precautionary measures against static discharge. |
P244 | Keep reduction valves free from grease and oil. |
P250 | Do not subject to grinding/shock/friction. |
P251 | Pressurized container: Do not pierce or burn, even after use. |
P260 | Do not breathe dust/fume/gas/mist/vapours/spray. |
P261 | Avoid breathing dust/fume/gas/mist/vapours/spray. |
P262 | Do not get in eyes, on skin, or on clothing. |
P263 | Avoid contact during pregnancy/while nursing. |
P264 | Wash hands thoroughly after handling. |
P265 | Wash skin thouroughly after handling. |
P270 | Do not eat, drink or smoke when using this product. |
P271 | Use only outdoors or in a well-ventilated area. |
P272 | Contaminated work clothing should not be allowed out of the workplace. |
P273 | Avoid release to the environment. |
P280 | Wear protective gloves/protective clothing/eye protection/face protection. |
P281 | Use personal protective equipment as required. |
P282 | Wear cold insulating gloves/face shield/eye protection. |
P283 | Wear fire/flame resistant/retardant clothing. |
P284 | Wear respiratory protection. |
P285 | In case of inadequate ventilation wear respiratory protection. |
P231 + P232 | Handle under inert gas. Protect from moisture. |
P235 + P410 | Keep cool. Protect from sunlight. |
Response | |
Code | Phrase |
P301 | IF SWALLOWED: |
P304 | IF INHALED: |
P305 | IF IN EYES: |
P306 | IF ON CLOTHING: |
P307 | IF exposed: |
P308 | IF exposed or concerned: |
P309 | IF exposed or if you feel unwell: |
P310 | Immediately call a POISON CENTER or doctor/physician. |
P311 | Call a POISON CENTER or doctor/physician. |
P312 | Call a POISON CENTER or doctor/physician if you feel unwell. |
P313 | Get medical advice/attention. |
P314 | Get medical advice/attention if you feel unwell. |
P315 | Get immediate medical advice/attention. |
P320 | |
P302 + P352 | IF ON SKIN: wash with plenty of soap and water. |
P321 | |
P322 | |
P330 | Rinse mouth. |
P331 | Do NOT induce vomiting. |
P332 | IF SKIN irritation occurs: |
P333 | If skin irritation or rash occurs: |
P334 | Immerse in cool water/wrap n wet bandages. |
P335 | Brush off loose particles from skin. |
P336 | Thaw frosted parts with lukewarm water. Do not rub affected area. |
P337 | If eye irritation persists: |
P338 | Remove contact lenses, if present and easy to do. Continue rinsing. |
P340 | Remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P341 | If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P342 | If experiencing respiratory symptoms: |
P350 | Gently wash with plenty of soap and water. |
P351 | Rinse cautiously with water for several minutes. |
P352 | Wash with plenty of soap and water. |
P353 | Rinse skin with water/shower. |
P360 | Rinse immediately contaminated clothing and skin with plenty of water before removing clothes. |
P361 | Remove/Take off immediately all contaminated clothing. |
P362 | Take off contaminated clothing and wash before reuse. |
P363 | Wash contaminated clothing before reuse. |
P370 | In case of fire: |
P371 | In case of major fire and large quantities: |
P372 | Explosion risk in case of fire. |
P373 | DO NOT fight fire when fire reaches explosives. |
P374 | Fight fire with normal precautions from a reasonable distance. |
P376 | Stop leak if safe to do so. Oxidising gases (section 2.4) 1 |
P377 | Leaking gas fire: Do not extinguish, unless leak can be stopped safely. |
P378 | |
P380 | Evacuate area. |
P381 | Eliminate all ignition sources if safe to do so. |
P390 | Absorb spillage to prevent material damage. |
P391 | Collect spillage. Hazardous to the aquatic environment |
P301 + P310 | IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
P301 + P312 | IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. |
P301 + P330 + P331 | IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. |
P302 + P334 | IF ON SKIN: Immerse in cool water/wrap in wet bandages. |
P302 + P350 | IF ON SKIN: Gently wash with plenty of soap and water. |
P303 + P361 + P353 | IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. |
P304 + P312 | IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell. |
P304 + P340 | IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. |
P304 + P341 | IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P305 + P351 + P338 | IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
P306 + P360 | IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes. |
P307 + P311 | IF exposed: call a POISON CENTER or doctor/physician. |
P308 + P313 | IF exposed or concerned: Get medical advice/attention. |
P309 + P311 | IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician. |
P332 + P313 | IF SKIN irritation occurs: Get medical advice/attention. |
P333 + P313 | IF SKIN irritation or rash occurs: Get medical advice/attention. |
P335 + P334 | Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages. |
P337 + P313 | IF eye irritation persists: Get medical advice/attention. |
P342 + P311 | IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician. |
P370 + P376 | In case of fire: Stop leak if safe to Do so. |
P370 + P378 | In case of fire: |
P370 + P380 | In case of fire: Evacuate area. |
P370 + P380 + P375 | In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion. |
P371 + P380 + P375 | In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion. |
Storage | |
Code | Phrase |
P401 | |
P402 | Store in a dry place. |
P403 | Store in a well-ventilated place. |
P404 | Store in a closed container. |
P405 | Store locked up. |
P406 | Store in corrosive resistant/ container with a resistant inner liner. |
P407 | Maintain air gap between stacks/pallets. |
P410 | Protect from sunlight. |
P411 | |
P412 | Do not expose to temperatures exceeding 50 oC/ 122 oF. |
P413 | |
P420 | Store away from other materials. |
P422 | |
P402 + P404 | Store in a dry place. Store in a closed container. |
P403 + P233 | Store in a well-ventilated place. Keep container tightly closed. |
P403 + P235 | Store in a well-ventilated place. Keep cool. |
P410 + P403 | Protect from sunlight. Store in a well-ventilated place. |
P410 + P412 | Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF. |
P411 + P235 | Keep cool. |
Disposal | |
Code | Phrase |
P501 | Dispose of contents/container to ... |
P502 | Refer to manufacturer/supplier for information on recovery/recycling |
Physical hazards | |
Code | Phrase |
H200 | Unstable explosive |
H201 | Explosive; mass explosion hazard |
H202 | Explosive; severe projection hazard |
H203 | Explosive; fire, blast or projection hazard |
H204 | Fire or projection hazard |
H205 | May mass explode in fire |
H220 | Extremely flammable gas |
H221 | Flammable gas |
H222 | Extremely flammable aerosol |
H223 | Flammable aerosol |
H224 | Extremely flammable liquid and vapour |
H225 | Highly flammable liquid and vapour |
H226 | Flammable liquid and vapour |
H227 | Combustible liquid |
H228 | Flammable solid |
H229 | Pressurized container: may burst if heated |
H230 | May react explosively even in the absence of air |
H231 | May react explosively even in the absence of air at elevated pressure and/or temperature |
H240 | Heating may cause an explosion |
H241 | Heating may cause a fire or explosion |
H242 | Heating may cause a fire |
H250 | Catches fire spontaneously if exposed to air |
H251 | Self-heating; may catch fire |
H252 | Self-heating in large quantities; may catch fire |
H260 | In contact with water releases flammable gases which may ignite spontaneously |
H261 | In contact with water releases flammable gas |
H270 | May cause or intensify fire; oxidizer |
H271 | May cause fire or explosion; strong oxidizer |
H272 | May intensify fire; oxidizer |
H280 | Contains gas under pressure; may explode if heated |
H281 | Contains refrigerated gas; may cause cryogenic burns or injury |
H290 | May be corrosive to metals |
Health hazards | |
Code | Phrase |
H300 | Fatal if swallowed |
H301 | Toxic if swallowed |
H302 | Harmful if swallowed |
H303 | May be harmful if swallowed |
H304 | May be fatal if swallowed and enters airways |
H305 | May be harmful if swallowed and enters airways |
H310 | Fatal in contact with skin |
H311 | Toxic in contact with skin |
H312 | Harmful in contact with skin |
H313 | May be harmful in contact with skin |
H314 | Causes severe skin burns and eye damage |
H315 | Causes skin irritation |
H316 | Causes mild skin irritation |
H317 | May cause an allergic skin reaction |
H318 | Causes serious eye damage |
H319 | Causes serious eye irritation |
H320 | Causes eye irritation |
H330 | Fatal if inhaled |
H331 | Toxic if inhaled |
H332 | Harmful if inhaled |
H333 | May be harmful if inhaled |
H334 | May cause allergy or asthma symptoms or breathing difficulties if inhaled |
H335 | May cause respiratory irritation |
H336 | May cause drowsiness or dizziness |
H340 | May cause genetic defects |
H341 | Suspected of causing genetic defects |
H350 | May cause cancer |
H351 | Suspected of causing cancer |
H360 | May damage fertility or the unborn child |
H361 | Suspected of damaging fertility or the unborn child |
H361d | Suspected of damaging the unborn child |
H362 | May cause harm to breast-fed children |
H370 | Causes damage to organs |
H371 | May cause damage to organs |
H372 | Causes damage to organs through prolonged or repeated exposure |
H373 | May cause damage to organs through prolonged or repeated exposure |
Environmental hazards | |
Code | Phrase |
H400 | Very toxic to aquatic life |
H401 | Toxic to aquatic life |
H402 | Harmful to aquatic life |
H410 | Very toxic to aquatic life with long-lasting effects |
H411 | Toxic to aquatic life with long-lasting effects |
H412 | Harmful to aquatic life with long-lasting effects |
H413 | May cause long-lasting harmful effects to aquatic life |
H420 | Harms public health and the environment by destroying ozone in the upper atmosphere |
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