Select Region or Location
Americas
  • Argentina
  • Brazil
  • Canada
  • Mexico
  • United States
  • Other Americas
Europe
  • Austria
  • Belgium
  • Bulgaria
  • Croatia/Hrvatska
  • Cyprus
  • Czech Republic
  • Denmark
  • Estonia
  • Finland
  • France
  • Germany
  • Greece
  • Hungary
  • Ireland
  • Italy
  • Latvia
  • Liechtenstein
  • Lithuania
  • Luxembourg
  • Malta
  • Netherlands
  • Norway
  • Poland
  • Portugal
  • Romania
  • Slovak Republic
  • Slovenia
  • Spain
  • Sweden
  • Switzerland
  • Turkey
  • United Kingdom
  • Other Europe
Asia Pacific
  • Australia
  • China
  • India
  • Indonesia
  • Japan
  • Korea, Republic of
  • Malaysia
  • New Zealand
  • Philippines
  • Singapore
  • Thailand
  • Vietnam
  • Other Asia Pacific
Africa And Middle East
  • Egypt
  • Israel
  • Other Africa And Middle East
USD
Home Cart Sign in  
Chemical Structure| 2569143-72-0 Chemical Structure| 2569143-72-0
Chemical Structure| 2569143-72-0

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only! Not for Human Use. We Do Not Sell to Patients.

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

DE Stock

US Stock

Asia Stock

Global Stock

In Stock
{[ item.pr_size ]}{[ size_append_text(item.pr_size, proInfo.prAm, 'list') ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

  • {[ item.pr_size ]}
    {[ size_append_text(item.pr_size, proInfo.prAm, 'list') ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of AZD-CO-Ph-PEG4-Ph-CO-AZD

CAS No. :2569143-72-0
Formula : C26H28N2O8
M.W : 496.51
SMILES Code : O=C(C1=CC=C(OCCOCCOCCOC2=CC=C(C=C2)C(=O)N3C(=O)CC3)C=C1)N4C(=O)CC4
English Name :1,1'-(4,4'-(((Ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl))bis(oxy))bis(benzoyl))bis(azetidin-2-one)

Safety of AZD-CO-Ph-PEG4-Ph-CO-AZD

Application In Synthesis of AZD-CO-Ph-PEG4-Ph-CO-AZD

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 2569143-72-0 ]

[ 2569143-72-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 930-21-2 ]
  • [ 105744-17-0 ]
  • [ 2569143-72-0 ]
YieldReaction ConditionsOperation in experiment
51% With dmap; triethylamine In dichloromethane at -78 - 20℃; for 24.25h; Inert atmosphere; Synthesis of Triethyiene glycol bis(l-[4-oxybenzoy)]-2-azetidinone) (15): The synthesis of bis-2-azetidinone derivative 15 was performed by analogy to published procedure of triethylamine-catalyzed coupling of 2-azetidinones with acyl chlorides.33A solution of commercial 2-azetidinone (0.57 g, 8 mmol) in anhyd. DCM (20 mL) was cooled to -78 °C under Ar atmosphere, and DMAP (0.1 g, 0.8 mmol) was added. A solution of dichloride 27 (1.72 g, 4 mmol) in anhyd. DCM (10 mL) was added via cannula for 5 min followed by dropwise addition of trieth lamine (1.0 mL, 7.2 mmol) for 10 min. The mixture was stirred at -78 °C for Ih, the cooling bath was removed, the mixture was stirred at rt for 23 h, diluted with DCM ( 10 mL) and quenched by addition of water (50 mL). The organic phase was separated, washed consecutively with water (50 mL), saturated NaCl, and dried over anhyd. Na SOv lire solvent was evaporated in vacuum to afford 1.73 g of crude residue. Chromatography of the residue over a flash column of silica gel with isocratic 80% AcOEt in hexanes gave 1.01 g (51%) of 15 as a white solid. 'HNMR (400 MHz, CD3CN): 3.02 (t , J = 5.6 Hz, 4H); 3.64 (t, J = 5.5 Hz, 4H); 3.65 (s, 4H); 3.79 (dd, J = 3.1, 4.6 Hz, 4H); 4.16 (dd, J = 3.2, 4.5 Hz, 4H); 6.97 (d split, J = 9.0 Hz, 4H); 7.91 (d split, J = 9.0 Hz, 4H).13C NMR (126 MHz, CD3CN): d 35.7; 37.6; 68.8; 70.2; 71.4; 114.9; 125.9; 132.9; 163.7; 165.9; 166.2. MS (ES+APCI) pos. scan [M + H]+= calc exact 497.1924; found: 497.2. HRMS: [M + H]+calc for C26H29N2O8, 497.1924, found: 497.1945.
 

Historical Records

Categories