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Chemical Structure| 537034-17-6 Chemical Structure| 537034-17-6

Structure of BML-210
CAS No.: 537034-17-6

Chemical Structure| 537034-17-6

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BML-210 is the HDAC inhibitor, and its mechanism of action has not been characterized.

Synonyms: N-phenyl-N'-(2-Aminophenyl)hexamethylenediamide; CAY10433

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Product Details of BML-210

CAS No. :537034-17-6
Formula : C20H25N3O2
M.W : 339.43
SMILES Code : O=C(NC1=CC=CC=C1N)CCCCCCC(NC2=CC=CC=C2)=O
Synonyms :
N-phenyl-N'-(2-Aminophenyl)hexamethylenediamide; CAY10433
MDL No. :MFCD08062139
InChI Key :RFLHBLWLFUFFDZ-UHFFFAOYSA-N
Pubchem ID :9543540

Safety of BML-210

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H361-H372-H410
Precautionary Statements:P201-P264-P280-P301+P330+P331-P312
Class:9
UN#:3077
Packing Group:

Related Pathways of BML-210

epigenetics

Isoform Comparison

Biological Activity

Description
BML-210 acts as a strong inhibitor of HDAC, able to suppress the HDAC4-VP16-driven reporter activity with an IC50 of approximately 5 µM. It specifically disrupts the HDAC4:MEF2 interaction, leads to an accumulation of cells in the G0/G1 phase, and promotes apoptosis, demonstrating antitumor efficacy in orthotopic mammary tumors in mice[1].[2].[3].

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Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.95mL

0.59mL

0.29mL

14.73mL

2.95mL

1.47mL

29.46mL

5.89mL

2.95mL

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