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Chemical Structure| 117467-28-4 Chemical Structure| 117467-28-4

Structure of Cefditoren pivoxil
CAS No.: 117467-28-4

Chemical Structure| 117467-28-4

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Cefditoren Pivoxil is a third-generation oral cephalosporin with a broad spectrum of activity against pathogens, including both Gram-positive and -negative bacteria, and is stable to hydrolysis by many common β-lactamases.

Synonyms: Cefditoren (Pivoxil); Cefditoren pivoxyl; ME 1207

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Product Details of Cefditoren pivoxil

CAS No. :117467-28-4
Formula : C25H28N6O7S3
M.W : 620.72
SMILES Code : O=C(C(N12)=C(/C=C\C3=C(C)N=CS3)CS[C@]2([H])[C@H](NC(/C(C4=CSC(N)=N4)=N\OC)=O)C1=O)OCOC(C(C)(C)C)=O
Synonyms :
Cefditoren (Pivoxil); Cefditoren pivoxyl; ME 1207
MDL No. :MFCD00933166

Safety of Cefditoren pivoxil

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H317
Precautionary Statements:P261-P280

Isoform Comparison

Biological Activity

Description
Cefditoren Pivoxil (ME 1207) is classified as a third-generation, broad-spectrum oral cephalosporin antibiotic that exhibits enhanced resistance to many common β-lactamases. It demonstrates activity against both Gram-negative and Gram-positive organisms, making it applicable in the study and treatment of infectious diseases like acute exacerbations of chronic bronchitis, community-acquired pneumonia (CAP), streptococcal pharyngitis/tonsillitis, and uncomplicated skin and skin structure infections[1].[2].

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT00598403 Urinary Tract Infections Phase 3 Completed - Greece ... More >> General Hospital of Chest Disease of Athens Athens, Greece General Hospital of Thessaloniki Thessaloniki, Greece Spain CS Rincón de Loix Benidorm, Alicante, Spain, 03500 CAP Cornella Cornella de Llobregat, Barcelona, Spain, 08940 CAP 17 setembre El Prat de Llobregat, Barcelona, Spain, 08820 CAP Bartomeu Fabres Anglada Gava, Barcelona, Spain, 08850 CAP Amadeu Torner Hospitalet de Llobregat, Barcelona, Spain, 08902 CAP Florida Nord Hospitalet de Llobregat, Barcelona, Spain, 08905 CAP Dr. Vicens Papaceit La Roca del Valles, Barcelona, Spain, 08430 CAP Les Bases-Manresa 3 Manresa, Barcelona, Spain, 08243 CAP La Riera Mataro, Barcelona, Spain, 08302 CAP El Maresme Mataro, Barcelona, Spain, 08303 CAP Navas-Balsareny Navas, Barcelona, Spain, 08670 CAP Remei Vic, Barcelona, Spain, 08500 CS San Telmo Jerez de la frontera, Cadiz, Spain, 11408 CS Cabra Cabra, Cordoba, Spain, 14940 CS Lucena Lucena, Cordoba, Spain, 14900 CS Rute Rute, Cordoba, Spain, 14960 CS Billabona Billabona, Guipuzcoa, Spain, 20150 CS Legazpi Legazpi, Guipuzcoa, Spain, 20230 CS Monzón Urbano Monzon, Huesca, Spain, 22400 CS Basurto Bilbao, Vizcaya, Spain, 48013 CS Cabo Huertas Alicante, Spain, 03540 CAP El Clot Barcelona, Spain, 08018 Fundacion Puigvert Barcelona, Spain, 08025 CS Sagasta Ruiseñores Zaragoza, Spain, 50006 CS Torrero La Paz Zaragoza, Spain, 50007 CS Torre Ramona Zaragoza, Spain, 50013 CS Arrabal Zaragoza, Spain, 50015 CS Bombarda Zaragoza, Spain, 50017 Less <<
NCT01553006 Rhinosinusitis Phase 4 Unknown September 2012 Thailand ... More >> Thammasat University Recruiting Prathumthani, Thailand, 12120 Contact: Orapan Poachanukoon, MD.    66819316781    orapanpoachanukoon@yahoo.com Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.61mL

0.32mL

0.16mL

8.06mL

1.61mL

0.81mL

16.11mL

3.22mL

1.61mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

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