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Chemical Structure| 2471982-20-2 Chemical Structure| 2471982-20-2

Structure of CU-115
CAS No.: 2471982-20-2

Chemical Structure| 2471982-20-2

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CU-115 is a highly efficient TLR8 antagonist with an IC50 of 1.04 µM, demonstrating high selectivity for TLR8 (IC50 > 50 µM for TLR7) and inhibiting TNF-α and IL-1β production in R-848-activated THP-1 cells.

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Product Details of CU-115

CAS No. :2471982-20-2
Formula : C21H11F7INO2
M.W : 569.21
SMILES Code : O=C(C1=C(C=CC=C1F)I)NC2=CC=C(C=C2)OC3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3
MDL No. :MFCD32868997

Safety of CU-115

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Related Pathways of CU-115

pyroptosis
TLR

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.76mL

0.35mL

0.18mL

8.78mL

1.76mL

0.88mL

17.57mL

3.51mL

1.76mL

 

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