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Chemical Structure| 1609564-75-1 Chemical Structure| 1609564-75-1

Structure of DY268
CAS No.: 1609564-75-1

Chemical Structure| 1609564-75-1

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DY268 is a potent antagonist of farnesoid X receptor (FXR), with an IC50 of 7.5 nM in time-resolved FRET analysis, inhibiting FXR transactivation with an IC50 of 468 nM, suitable for research related to metabolic diseases.

4.5 *For Research Use Only! Not for Human Use. We Do Not Sell to Patients.

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Product Details of DY268

CAS No. :1609564-75-1
Formula : C30H32N4O5S
M.W : 560.66
SMILES Code : CC1=C(S(N2CCOCC2)(=O)=O)C=C(NC(C3=CN(CC4=CC(OC)=CC=C4)N=C3C5=CC=C(C)C=C5)=O)C=C1
English Name :1-(3-Methoxybenzyl)-N-(4-methyl-3-(morpholinosulfonyl)phenyl)-3-(p-tolyl)-1H-pyrazole-4-carboxamide
MDL No. :MFCD30182341

Safety of DY268

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.78mL

0.36mL

0.18mL

8.92mL

1.78mL

0.89mL

17.84mL

3.57mL

1.78mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

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