Home Cart Sign in  
Chemical Structure| 848249-10-5 Chemical Structure| 848249-10-5

Structure of HS-243
CAS No.: 848249-10-5

Chemical Structure| 848249-10-5

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

HS-243 is an effective and selective IRAK-4 and IRAK-1 inhibitor with anti-inflammatory and anticancer activities, showing weak inhibitory effects on TAK1, used in related disease research.

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of HS-243

CAS No. :848249-10-5
Formula : C17H16N4O3
M.W : 324.33
SMILES Code : CCCN1C(NC(C2=CC([N+]([O-])=O)=CC=C2)=O)=NC3=CC=CC=C13
MDL No. :N/A
InChI Key :JLLIANWHDQWCMY-UHFFFAOYSA-N
Pubchem ID :4800865

Safety of HS-243

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Related Pathways of HS-243

Hedgehog
TLR

Isoform Comparison

Biological Activity

Description
HS-243 is a potent and selective inhibitor of IRAK-4 and IRAK-1, with IC50 values of 20 nM and 24 nM, respectively. It exhibits minimal inhibition of TAK1 (transforming growth factor β-activated kinase 1), with an IC50 of 0.5 µM. HS-243 demonstrates anti-inflammatory and anticancer properties[1].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.08mL

0.62mL

0.31mL

15.42mL

3.08mL

1.54mL

30.83mL

6.17mL

3.08mL

References

 

Historical Records

Categories