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P01024-Human C3a-3d structure.jpg P01024-Human C3a-3d structure.jpg

Human C3a+SDS-PAGE.jpg Human C3a+SDS-PAGE.jpg Greater than 95% as determined by reducing SDS-PAGE.

Greater than 95% as determined by reducing SDS-PAGE.

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Recombinant Human C3a is a tag-free human recombinant protein expressed in Escherichia coli. As a cleavage product of the complement system component C3, it functions as a potent anaphylatoxin with strong immunostimulatory activity. By binding to the C3a receptor (C3aR), it enhances vascular permeability, induces mast cell degranulation, and activates leukocytes, playing a critical role in innate immune defense mechanisms against pathogen clearance.

Synonyms: Recombinant Human C3a; Complement Component C3a; C3a

4.5 *For Research Use Only! Not for Human Use. We Do Not Sell to Patients.

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Product Details of Human C3a

M.W : 9.1 KDa
SMILES Code : NONE
Synonyms :
Recombinant Human C3a; Complement Component C3a; C3a
English Name :Recombinant Human C3a

Safety of Human C3a

Isoform Comparison

Biological Activity

Description
Complement is defined as key part of innate immunity and as the first line of defense in the fight against invading pathogens. Complement 3 (C3) is the most abundant component of the complement cascade and the convergent point for all three major complement activation pathways: namely classical, alternative and mannose-binding lectin pathways. Complement activation leads to the formation of the C3 convertase, which cleaves C3 into the key effector molecules, C3a (anaphylatoxin) and C3b (opsonin) which then drive microbe removal. By binding to C3a receptor (C3aR), C3a exhibits potent anaphylatoxin activity, including increased vascular permeability, triggering degranulation of mast cells, inflammation, and activating leukocytes.
 

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