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P13501-Human CCL5-3d structure.jpg P13501-Human CCL5-3d structure.jpg

Human CCL5+SDS-PAGE.jpg Human CCL5+SDS-PAGE.jpg Greater than 95% as determined by reducing SDS-PAGE.

Greater than 95% as determined by reducing SDS-PAGE.

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Recombinant Human CCL5 is a tag-free human protein expressed in E. coli. It corresponds to the human chemokine (C-C motif) ligand 5, which plays a crucial role in recruiting leukocytes to inflammatory sites. Secreted by various cell types at inflammation loci, it exerts broad functions through binding to CCR1, CCR3, CCR4, and CCR5 receptors. Truncated forms of CCL5 may exhibit antagonistic or partial agonistic activities and are involved in multiple allergic and autoimmune diseases.

Synonyms: Recombinant Human CCL5; C-C Motif Chemokine 5; EoCP

4.5 *For Research Use Only! Not for Human Use. We Do Not Sell to Patients.

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Product Details of Human CCL5

M.W : 7.8 KDa
SMILES Code : NONE
Synonyms :
Recombinant Human CCL5; C-C Motif Chemokine 5; EoCP
English Name :Recombinant Human CCL5

Safety of Human CCL5

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Biological Activity

Description
Human Chemokine (C-C Motif) Ligand 5 (CCL5) plays an active role in recruiting leukocytes into inflammatory sites. CCL5 is secreted by many cell types at inflammatory sites and it exerts a wide range of activities through the receptors CCR1, CCR3, CCR4, and CCR5. N-Terminal truncated CCL5/RANTES, Met-RANTES, and amino-oxypentane (AOP)-RANTES exhibit antagonist or partial agonist functions on their receptors. CCL5/RANTES attracts different subtypes of leukocytes into inflamed tissue and intervenes in a wide range of allergic and autoimmune diseases.
 

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