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Human G-CSF+Cell Based Assay.jpg Human G-CSF+Cell Based Assay.jpg Induces proliferation in NFS-60 cells. ED50: 0.03 ng/ml (Regularly tested).

Induces proliferation in NFS-60 cells. ED50: 0.03 ng/ml (Regularly tested).

Human G-CSF+SDS-PAGE.jpg Human G-CSF+SDS-PAGE.jpg Greater than 95% as determined by reducing SDS-PAGE.

Greater than 95% as determined by reducing SDS-PAGE.

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Recombinant Human G-CSF is a human-derived protein expressed in E. coli without any tags. This 20 kD glycoprotein contains an internal disulfide bond and functions as the most potent terminal differentiation inducer within the granulocyte colony-stimulating factor family. It promotes the survival, proliferation, and differentiation of neutrophil precursors, and activates the function of mature neutrophils. Its synthesis is regulated by multiple factors.

Synonyms: Recombinant Human G-CSF; Granulocyte Colony-Stimulating Factor; G-CSF

4.5 *For Research Use Only! Not for Human Use. We Do Not Sell to Patients.

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Product Details of Human G-CSF

M.W : 18.8 KDa
SMILES Code : NONE
Synonyms :
Recombinant Human G-CSF; Granulocyte Colony-Stimulating Factor; G-CSF
English Name :Recombinant Human G-CSF

Safety of Human G-CSF

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Description
Human Granulocyte-Colony-Stimulating Factor (G-CSF) is 20 kD glycoprotein containing internal disulfide bonds. It induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and it functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines. The synthesis of G-CSF can be induced by bacterial endotoxins, TNF, Interleukin-1, and GM-CSF. Prostaglandin E2 inhibits the synthesis of G-CSF. In epithelial, endothelial, and fibroblastic cells secretion of G-CSF is induced by Interleukin-17.
 

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