Select Region or Location
Americas
  • Argentina
  • Brazil
  • Canada
  • Mexico
  • United States
  • Other Americas
Europe
  • Austria
  • Belgium
  • Bulgaria
  • Croatia/Hrvatska
  • Cyprus
  • Czech Republic
  • Denmark
  • Estonia
  • Finland
  • France
  • Germany
  • Greece
  • Hungary
  • Ireland
  • Italy
  • Latvia
  • Liechtenstein
  • Lithuania
  • Luxembourg
  • Malta
  • Netherlands
  • Norway
  • Poland
  • Portugal
  • Romania
  • Slovak Republic
  • Slovenia
  • Spain
  • Sweden
  • Switzerland
  • Turkey
  • United Kingdom
  • Other Europe
Asia Pacific
  • Australia
  • China
  • India
  • Indonesia
  • Japan
  • Korea, Republic of
  • Malaysia
  • New Zealand
  • Philippines
  • Singapore
  • Thailand
  • Vietnam
  • Other Asia Pacific
Africa And Middle East
  • Egypt
  • Israel
  • Other Africa And Middle East
USD
Home Cart Sign in  
Chemical Structure| 1426047-44-0 Chemical Structure| 1426047-44-0

Structure of IND24
CAS No.: 1426047-44-0

Chemical Structure| 1426047-44-0

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

IND24 is an antiprion agent that reduces intracellular misfolded pathogenic prion proteins, with an EC50 value of 1.27 µM. It is applicable for research on neurodegenerative diseases.

4.5 *For Research Use Only! Not for Human Use. We Do Not Sell to Patients.

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

DE Stock

US Stock

Asia Stock

Global Stock

In Stock
{[ item.pr_size ]}{[ size_append_text(item.pr_size, proInfo.prAm, 'list') ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

  • {[ item.pr_size ]}
    {[ size_append_text(item.pr_size, proInfo.prAm, 'list') ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of IND24

CAS No. :1426047-44-0
Formula : C21H17N3S
M.W : 343.44
SMILES Code : CC1=CC=CC(NC2=NC(C3=CC=C(C4=CC=CC=C4)C=C3)=CS2)=N1
English Name :IND24

Safety of IND24

Isoform Comparison

Biological Activity

In Vivo:

Species
Animal Model
Administration Dosage Frequency Description References
Transgenic mice Chronic wasting disease (CWD) and scrapie models Oral (via liquid diet) 50–210 mg/kg/day Continuous treatment until disease onset To evaluate the therapeutic efficacy of IND24 against CWD and scrapie prions, results showed that IND24 significantly extended the survival of CWD-infected mice but had no effect on scrapie-infected mice. J Infect Dis. 2015 Jul 15;212 Suppl 1(Suppl 1):S17-25

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.91mL

0.58mL

0.29mL

14.56mL

2.91mL

1.46mL

29.12mL

5.82mL

2.91mL

 

Historical Records

Categories