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Chemical Structure| 23146-22-7 Chemical Structure| 23146-22-7

Structure of IQ-1S free acid
CAS No.: 23146-22-7

Chemical Structure| 23146-22-7

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IQ-1S Free Acid is a selective JNK3 inhibitor with IC50 value of 87 nM, with less potency against JNK 1/2 with IC50 values of 390/360nM.

Synonyms: IQ-1S (free acid); IQ-1S; IQ-1

4.5 *For Research Use Only! Not for Human Use. We Do Not Sell to Patients.

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Product Details of IQ-1S free acid

CAS No. :23146-22-7
Formula : C15H9N3O
M.W : 247.25
SMILES Code : O/N=C1C2=C(C3=NC4=CC=CC=C4N=C3\1)C=CC=C2
Synonyms :
IQ-1S (free acid); IQ-1S; IQ-1
English Name :11H-Indeno[1,2-b]quinoxalin-11-one oxime
MDL No. :MFCD00612483
InChI Key :YSYIWCNPSZNNKW-UHFFFAOYSA-N
Pubchem ID :619002

Safety of IQ-1S free acid

Related Pathways of IQ-1S free acid

MAPK
pyroptosis
TLR

Isoform Comparison

Biological Activity

Target
  • JNK1

    JNK1, IC50:390 nM

  • JNK2

    JNK2, IC50:360 nM

  • JNK3

    JNK3, IC50:87 nM

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

4.04mL

0.81mL

0.40mL

20.22mL

4.04mL

2.02mL

40.44mL

8.09mL

4.04mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

References

 

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