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Chemical Structure| 1632032-53-1 Chemical Structure| 1632032-53-1

Structure of LB-100
CAS No.: 1632032-53-1

Chemical Structure| 1632032-53-1

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LB-100 is a small-molecular protein phosphatase 2A (PP2A) inhibitor with IC50 of 0.85 μM and 3.87 μM in BxPc-3 and Panc-1 cells.

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Product Details of LB-100

CAS No. :1632032-53-1
Formula : C13H20N2O4
M.W : 268.31
SMILES Code : OC(C1C(C(N2CCN(C)CC2)=O)[C@]3([H])CC[C@]1(O3)[H])=O
MDL No. :MFCD28167839

Safety of LB-100

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Isoform Comparison

Biological Activity

Description
LB-100, acting as an inhibitor of protein phosphatase 2A (PP2A), shows IC50 values of 0.85 μM and 3.87 μM in BxPc-3 and Panc-1 cells, respectively, indicating its potent inhibitory action[1].[2].[3].

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT03886662 Myelodysplastic Syndromes PHASE1|PHASE2 RECRUITING 2025-07-21 H. Lee Moffitt Cancer Center &... More >> Research Institute, Tampa, Florida, 33612, United States Less <<
NCT03027388 Astrocytoma, Grades II, III an... More >>d IV|Glioblastoma Multiforme|Giant Cell Glioblastoma|Glioma|Oligodendrogliomas Less << PHASE2 COMPLETED 2022-08-31 National Institutes of Health ... More >>Clinical Center, Bethesda, Maryland, 20892, United States Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.73mL

0.75mL

0.37mL

18.64mL

3.73mL

1.86mL

37.27mL

7.45mL

3.73mL

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