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Chemical Structure| 1702816-75-8 Chemical Structure| 1702816-75-8

Structure of Linperlisib
CAS No.: 1702816-75-8

Chemical Structure| 1702816-75-8

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Linperlisib (YY-20394) is an effective orally active, selectively PI3Kδ inhibitor with an IC50 of 6.4 nM.

Synonyms: YY-20394

4.5 *For Research Use Only !

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Product Details of Linperlisib

CAS No. :1702816-75-8
Formula : C28H37FN6O5S
M.W : 588.69
SMILES Code : CS(=O)(NC1=CC(C2=C3C=C(F)C=C(CN4CCC(C(C)(O)C)CC4)C3=NC(N5CCOCC5)=N2)=CN=C1OC)=O
Synonyms :
YY-20394
MDL No. :MFCD31544346

Safety of Linperlisib

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Related Pathways of Linperlisib

PI3K-AKT

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT05676697 Autoimmune Hemolytic Anemia|Fa... More >>ilure of Two Rounds of Treatment Less << PHASE1 TERMINATED 2024-02-06 Zhoukou Central Hospital, Zhou... More >>kou, Henan, China|Regenerative Medicine Center, Tianjin, Tianjin, China Less <<
NCT04379167 Follicular Lymphoma PHASE2 UNKNOWN 2022-12-30 -
NCT04049929 Advanced Solid Tumor PHASE1 UNKNOWN 2025-10-20 Shanghai East Hospital, Shangh... More >>ai, Shanghai, 200123, China Less <<
NCT03757000 B-cell Lymphoma Recurrent|B-ce... More >>ll Chronic Lymphocytic Leukemia Less << PHASE1 UNKNOWN 2019-05-30 Peking Cancer Hospital, Beijin... More >>g, Beijing, 100142, China|Jiangsu Province Hospital, Nanjing, Jiangsu, 210029, China|Hematology Hospital of Chinese Academy of Medical Sciences, Tianjin, Tianjin, 300020, China Less <<
NCT05863871 Focus on the Lymphoma Includin... More >>g B/T-cell Lymphoma Less << NOT_YET_RECRUITING 2025-06-27 Ruijin Hospital, Shanghai Jiao... More >> Tong University School of Medicine, Shanghai, China|Tianjin Cancer Hospital/ Tianjin medical university cancer institute & hospital, Tianjin, China Less <<
NCT05676710 Relapsed/Refractory Large Gran... More >>ular T Lymphocytic Leukemia Less << PHASE1 COMPLETED 2024-02-14 Zhoukou Central Hospital, Zhou... More >>kou, Henan, China|Regenerative Medicine Center, Tianjin, Tianjin, China Less <<
NCT05274997 Peripheral T/NK Cell Lymphoma ... More >>(R/R PTCL) Less << PHASE2 UNKNOWN 2023-12-01 MD Anderson Cancer Center, Hou... More >>ston, Texas, 77030, United States Less <<
NCT06548347 Peripheral T Cell Lymphoma PHASE2|PHASE3 NOT_YET_RECRUITING 2029-09-30 -
NCT06343935 Indolent B-cell Lymphoma PHASE4 NOT_YET_RECRUITING 2025-04-30 -
NCT06224257 Relapsed/Refractory Large Gran... More >>ular T Lymphocytic Leukemia Less << PHASE2 RECRUITING 2025-10-31 Anhui Provincial Hospital, Hef... More >>ei, Anhui, China|Zhoukou Central Hospital, Zhoukou, Henan, China|Regenerative Medicine Center, Tianjin, Tianjin, China Less <<
NCT04500561 Diffuse Large B Cell Lymphoma PHASE1|PHASE2 UNKNOWN 2021-12-01 -
NCT04975061 Effectiveness,Safety,Thymic Ca... More >>ncer Less << UNKNOWN 2022-12-30 -
NCT04108325 Relapsed or Refractory Periphe... More >>ral T-Cell Lymphoma Less << PHASE1 UNKNOWN 2025-12-21 Hematology Hospital of Chinese... More >> Academy of Medical Sciences, Tianjin, Tianjin, 3000, China Less <<
NCT04370405 Lymphoma, Follicular PHASE2 UNKNOWN 2021-02-22 Hematology Hospital of Chinese... More >> Academy of Medical Sciences, Tianjin, Tianjin, 3000, China Less <<
NCT04279405 Small Lymphocytic Lymphoma|Lym... More >>phoplasmacytic Lymphoma|Marginal Zone Lymphoma|Mantle Cell Lymphoma|Diffuse Large B Cell Lymphoma Less << PHASE1 COMPLETED 2023-06-01 Hematology Hospital of the Chi... More >>nese Academy of Medical Sciences, Tianjin, China Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.70mL

0.34mL

0.17mL

8.49mL

1.70mL

0.85mL

16.99mL

3.40mL

1.70mL

 

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