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Chemical Structure| 1049704-18-8 Chemical Structure| 1049704-18-8

Structure of MA242
CAS No.: 1049704-18-8

Chemical Structure| 1049704-18-8

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MA242 is a Dual Inhibitors of MDM2 and NFAT1 for Pancreatic Cancer Therapy. MA242 decreased cell proliferation and induced apoptosis in pancreatic cancer cell lines regardless of p53 status. MA242 alone or in combination with gemcitabine inhibited pancreatic tumor growth and metastasis without any host toxicity. Our data indicate that targeting both MDM2 and NFAT1 represents a novel and effective strategy to treat pancreatic cancer.

4.5 *For Research Use Only! Not for Human Use. We Do Not Sell to Patients.

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Product Details of MA242

CAS No. :1049704-18-8
Formula : C26H21ClF3N3O5S
M.W : 579.98
SMILES Code : CC1=CC=C(C=C1)S(N2C=C3CCN=C4C=C(NCC5=CC=C(Cl)C=C5)C(C2=C34)=O)(=O)=O.FC(F)(C(O)=O)F
English Name :7-((4-Chlorobenzyl)amino)-1-tosyl-3,4-dihydropyrrolo[4,3,2-de]quinolin-8(1H)-one 2,2,2-trifluoroacetate

Safety of MA242

Related Pathways of MA242

PI3K-AKT

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.72mL

0.34mL

0.17mL

8.62mL

1.72mL

0.86mL

17.24mL

3.45mL

1.72mL

 

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