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Chemical Structure| 1346233-68-8 Chemical Structure| 1346233-68-8

Structure of ML218
CAS No.: 1346233-68-8

Chemical Structure| 1346233-68-8

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ML218 is a potent, selective, and orally active T-type Ca²⁺ channel inhibitor with IC50 values of 310 nM and 270 nM for Cav3.2 and Cav3.3, respectively. It inhibits burst firing of neurons in the subthalamic nucleus (STN) and can penetrate the blood-brain barrier.

4.5 *For Research Use Only! Not for Human Use. We Do Not Sell to Patients.

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Product Details of ML218

CAS No. :1346233-68-8
Formula : C19H26Cl2N2O
M.W : 369.33
SMILES Code : O=C(NC[C@H]1[C@]2([H])CN(CCC(C)(C)C)C[C@]12[H])C3=CC(Cl)=CC(Cl)=C3
English Name :rel-3,5-Dichloro-N-(((1R,5S,6s)-3-(3,3-dimethylbutyl)-3-azabicyclo[3.1.0]hexan-6-yl)methyl)benzamide
MDL No. :MFCD23704169

Safety of ML218

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.71mL

0.54mL

0.27mL

13.54mL

2.71mL

1.35mL

27.08mL

5.42mL

2.71mL

 

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