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Chemical Structure| 2579689-83-9 Chemical Structure| 2579689-83-9

Structure of ML339
CAS No.: 2579689-83-9

Chemical Structure| 2579689-83-9

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ML339 is a selective CXCR6 antagonist with an IC50 of 140 nM. It antagonizes β-arrestin recruitment and cAMP signaling in human CXCR6 receptors induced by CXCL16, with IC50 values of 0.3 μM and 1.4 μM, respectively. ML339 has weaker activity against β-arrestin recruitment in mouse CXCR6 receptors, with an IC50 of 18 μM. ML339 does not inhibit CXCR5, CXCR4, CXCR6, or the Apelin receptor (APJ), with IC50 >79 μM.

4.5 *For Research Use Only! Not for Human Use. We Do Not Sell to Patients.

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Product Details of ML339

CAS No. :2579689-83-9
Formula : C26H32ClN3O5
M.W : 502.00
SMILES Code : C(C(NC1=C(Cl)C=CC=C1)=O)N2[C@@]3(C[C@H](NC(=O)C4=CC(OC)=C(OC)C(OC)=C4)C[C@]2(CCC3)[H])[H]
English Name :(3-exo)-N-(9-(2-((2-Chlorophenyl)amino)-2-oxoethyl)-9-azabicyclo[3.3.1]nonan-3-yl)-3,4,5-trimethoxybenzamide
MDL No. :MFCD30720892

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1.99mL

 

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