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P84444-Mouse CCL21-3d structure.jpg P84444-Mouse CCL21-3d structure.jpg

Mouse CCL21+SDS-PAGE.jpg Mouse CCL21+SDS-PAGE.jpg Greater than 95% as determined by reducing SDS-PAGE.

Greater than 95% as determined by reducing SDS-PAGE.

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Recombinant Mouse CCL21 is a tag-free protein expressed in E. coli, derived from mouse sources. It corresponds to C-C motif chemokine 21a (CCL21a), a member of the CC chemokine family, with a mature protein consisting of 110 amino acids, featuring the unique Ser-65 residue specific to CCL21a. This protein can bind to CCR7 and CXCR3, exhibiting chemotactic activity that promotes the migration of naïve T cells, inhibits hematopoiesis, and plays a role in lymphocyte homing to secondary lymphoid organs.

Synonyms: Recombinant Mouse CCL21; C-C Motif Chemokine 21a; 6Ckine

4.5 *For Research Use Only! Not for Human Use. We Do Not Sell to Patients.

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Product Details of Mouse CCL21

M.W : 12.1 KDa
SMILES Code : NONE
Synonyms :
Recombinant Mouse CCL21; C-C Motif Chemokine 21a; 6Ckine
English Name :Recombinant Mouse CCL21

Safety of Mouse CCL21

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Description
C-C Motif Chemokine 21a (CCL21a) is a small secreted cytokine that belongs to the intercrine beta (CC chemokine) family. Mouse CCL21 cDNA encodes a 133 amino acid residue protein with a 23 residue signal peptide that is cleaved to generate the 110 residue mature protein. Mouse CCL21 has three forms while CCL21a has Ser-65. CCL21 elicits its effects by binding to a cell surface chemokine receptor known as CCR7 and CXCR3. Mouse CCL21 inhibits hemopoiesis and stimulates chemotaxis. It has chemotactic function in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Mouse CCL21 shows preferential activity towards naive T-cells and may play a role in mediating homing of lymphocytes to secondary lymphoid organs.
 

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