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P01587-Mouse GM-CSF-3d structure.jpg P01587-Mouse GM-CSF-3d structure.jpg

Mouse GM-CSF+Cell Based Assay.jpg Mouse GM-CSF+Cell Based Assay.jpg Induces proliferation in FDC-P1 cells. ED50: 15-50 pg/ml (QC verified).

Induces proliferation in FDC-P1 cells. ED50: 15-50 pg/ml (QC verified).

Mouse GM-CSF+SDS-PAGE.jpg Mouse GM-CSF+SDS-PAGE.jpg Greater than 95% as determined by reducing SDS-PAGE.

Greater than 95% as determined by reducing SDS-PAGE.

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Recombinant Mouse GM-CSF is a tag-free protein derived from mouse and expressed in E. coli. This protein, also known as granulocyte-macrophage colony-stimulating factor, was initially identified as a growth factor supporting the formation of granulocyte-macrophage colonies from progenitor cells in vitro. It is produced by various cell types in response to immune and inflammatory stimuli, and promotes the growth of multiple progenitor cell types. In addition, it exerts functional effects on mature hematopoietic cells as well as non-hematopoietic cells.

Synonyms: Recombinant Mouse GM-CSF; Granulocyte-macrophage colony-stimulating factor; Csf2

4.5 *For Research Use Only! Not for Human Use. We Do Not Sell to Patients.

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Product Details of Mouse GM-CSF

M.W : 14.2 KDa
SMILES Code : NONE
Synonyms :
Recombinant Mouse GM-CSF; Granulocyte-macrophage colony-stimulating factor; Csf2
English Name :Recombinant Mouse GM-CSF

Safety of Mouse GM-CSF

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Description
Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factorthat can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by anumber of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cellsand fibroblasts) in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophageprogenitors, GM-CSF is also a growth factor for erythroid, megakaryocyte and eosinophil progenitors. Onmature hematopoietic, monocytes/ macrophages and eosinophils. GM-CSF has a functional role on nonhematopoitic cells. It can induce human endothelial cells to migrate and proliferate. Additionally, GM-CSF canalso stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma andadenocarcinoma cell lines.
 

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