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P07141-Mouse M-CSF-3d structure.jpg P07141-Mouse M-CSF-3d structure.jpg

Mouse M-CSF+Cell Based Assay.jpg Mouse M-CSF+Cell Based Assay.jpg Induces proliferation in M-NFS-60 cells. ED50: 0.04-0.2 ng/ml (QC verified).

Induces proliferation in M-NFS-60 cells. ED50: 0.04-0.2 ng/ml (QC verified).

Mouse M-CSF+SDS-PAGE.jpg Mouse M-CSF+SDS-PAGE.jpg Greater than 95% as determined by reducing SDS-PAGE.

Greater than 95% as determined by reducing SDS-PAGE.

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Recombinant Mouse M-CSF is a tag-free protein expressed in human cells, derived from mouse. This protein, also known as Macrophage Colony-Stimulating Factor 1 (M-CSF1), is a type I single-pass transmembrane protein functioning as a hematopoietic growth factor. It plays critical roles in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. Additionally, it enhances phagocytic and chemotactic activities of macrophages and monocytes, as well as tumor cell cytotoxicity. M-CSF also influences the proliferation of early hematopoietic progenitors and is involved in various physiological processes including immunity, metabolism, fertility, and pregnancy.

Synonyms: Recombinant Mouse M-CSF; Macrophage colony-stimulating factor 1; CSF-1

4.5 *For Research Use Only! Not for Human Use. We Do Not Sell to Patients.

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Product Details of Mouse M-CSF

M.W : 26 KDa
SMILES Code : NONE
Synonyms :
Recombinant Mouse M-CSF; Macrophage colony-stimulating factor 1; CSF-1
English Name :Recombinant Mouse M-CSF

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Description
Macrophage colony-stimulating factor 1(M-csf)is a single-pass type I membrane protein . It is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. M-CSF affects macrophages and monocytes in several ways, including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. The role of M-CSF is not only restricted to the monocyte/macrophage cell lineage. By interacting with its membrane receptor, M-CSF also modulates the proliferation of earlier hematopoietic progenitors and influence numerous physiological processes involved in immunology, metabolism, fertility and pregnancy.
 

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