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Chemical Structure| 51551-29-2 Chemical Structure| 51551-29-2

Structure of Neoechinulin A
CAS No.: 51551-29-2

Chemical Structure| 51551-29-2

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Neoechinulin A, a natural product isolated and purified from Aspergillus chevalieri with anti-inflammatory effect against LPS-stimulated RAW264.7 macrophages through inhibition of the NF-κB and p38 MAPK pathways, may block the phosphorylation of mitogen-activated protein kinase (MAPK) molecule p38, apoptosis signal-regulating kinase 1 (ASK-1) and nuclear translocation of nuclear factor-κB (NF-κB) p65 and p50 subunits, and ameliorate rotenone toxicity by activating a cytoprotective machinery that requires ATP and antioxidant/anti-nitration activities.

4.5 *For Research Use Only! Not for Human Use. We Do Not Sell to Patients.

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Product Details of Neoechinulin A

CAS No. :51551-29-2
Formula : C19H21N3O2
M.W : 323.39
SMILES Code : O=C(/C(N1)=C/C2=C(C(C)(C)C=C)NC3=C2C=CC=C3)N[C@@H](C)C1=O
English Name :(S,Z)-3-Methyl-6-((2-(2-methylbut-3-en-2-yl)-1H-indol-3-yl)methylene)piperazine-2,5-dione
MDL No. :MFCD09752743

Safety of Neoechinulin A

Related Pathways of Neoechinulin A

GPCR
MAPK
pyroptosis
TLR

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.09mL

0.62mL

0.31mL

15.46mL

3.09mL

1.55mL

30.92mL

6.18mL

3.09mL

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