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Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 465-16-7 Chemical Structure| 465-16-7

Structure of Oleandrin
CAS No.: 465-16-7

Chemical Structure| 465-16-7

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Oleandrin, a natural product isolated and purified from the herbs of Nerium oleander L., inhibits the activity of NF-κB in various cultured cell lines (U937, CaOV3, human epithelial cells and T cells) as well as it induces programmed cell death in PC3 cell line culture.

Synonyms: PBI-05204; Folinerin; Neriol

4.5 *For Research Use Only !

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Product Details of Oleandrin

CAS No. :465-16-7
Formula : C32H48O9
M.W : 576.72
SMILES Code : O=C1OCC([C@H]2[C@@H](OC(C)=O)C[C@]3(O)[C@]4([H])CC[C@]5([H])C[C@@H](O[C@H]6C[C@@H]([C@H]([C@H](C)O6)O)OC)CC[C@]5(C)[C@@]4([H])CC[C@]23C)=C1
Synonyms :
PBI-05204; Folinerin; Neriol
MDL No. :MFCD00079204
InChI Key :JLPDBLFIVFSOCC-XYXFTTADSA-N
Pubchem ID :11541511

Safety of Oleandrin

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H300+H330-H373
Precautionary Statements:P260-P264-P284-P301+P310-P310
Class:6.1
UN#:2811
Packing Group:

Related Pathways of Oleandrin

pyroptosis

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT00554268 Solid Tumors PHASE1 COMPLETED 2025-04-13 UT MD Anderson Cancer Center, ... More >>Houston, Texas, 77030, United States Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.73mL

0.35mL

0.17mL

8.67mL

1.73mL

0.87mL

17.34mL

3.47mL

1.73mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

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