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Chemical Structure| 153168-05-9 Chemical Structure| 153168-05-9

Structure of Pleconaril
CAS No.: 153168-05-9

Chemical Structure| 153168-05-9

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Pleconaril is a capsid inhibitor used previously to treat enterovirus infections. Pleconaril is effective in inhibiting replication with an IC50 of 50 nM.

Synonyms: VP 63843;Win 63843;SR-63843

4.5 *For Research Use Only! Not for Human Use. We Do Not Sell to Patients.

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Product Details of Pleconaril

CAS No. :153168-05-9
Formula : C18H18F3N3O3
M.W : 381.35
SMILES Code : FC(C1=NC(C2=CC(C)=C(OCCCC3=CC(C)=NO3)C(C)=C2)=NO1)(F)F
Synonyms :
VP 63843;Win 63843;SR-63843
English Name :3-(3,5-Dimethyl-4-(3-(3-methylisoxazol-5-yl)propoxy)phenyl)-5-(trifluoromethyl)-1,2,4-oxadiazole
MDL No. :MFCD00923611
InChI Key :KQOXLKOJHVFTRN-UHFFFAOYSA-N
Pubchem ID :1684

Safety of Pleconaril

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT00031512 Enteroviral Sepsis Phase 2 Completed - -
NCT00394914 Asthma Common... More >> Cold Picornavirus Infection Rhinovirus Less << Phase 2 Completed - -
NCT00394914 - Completed - -

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.62mL

0.52mL

0.26mL

13.11mL

2.62mL

1.31mL

26.22mL

5.24mL

2.62mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

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