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Chemical Structure| 2407433-00-3 Chemical Structure| 2407433-00-3

Structure of T025
CAS No.: 2407433-00-3

Chemical Structure| 2407433-00-3

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T025 is an orally active CLK (Cdc2-like kinase) inhibitor with nanomolar Kd values for various CLK kinase subtypes (e.g., CLK2 is 0.096 nM). T025 can induce caspase-3/7 mediated apoptosis, suitable for research on MYC-driven tumors and diseases associated with abnormal cell proliferation.

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Product Details of T025

CAS No. :2407433-00-3
Formula : C21H18N8
M.W : 382.42
SMILES Code : N=1C=CC=NC1CNC=2N=C(N=C3NC=C(C=4C=CC=5N=CC=CC5C4)C32)NC
MDL No. :MFCD31813666
InChI Key :PMWVYONICYRLNY-UHFFFAOYSA-N
Pubchem ID :133082038

Safety of T025

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Related Pathways of T025

RTK
PI3K-AKT
Hedgehog

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.61mL

0.52mL

0.26mL

13.07mL

2.61mL

1.31mL

26.15mL

5.23mL

2.61mL

Dissolving Methods
The prepared working fluid is recommended to be prepared now and used up as soon as possible in a short period of time. The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1

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