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Chemical Structure| 1257051-63-0 Chemical Structure| 1257051-63-0

Structure of THPP-1
CAS No.: 1257051-63-0

Chemical Structure| 1257051-63-0

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THPP-1 is a potent and selective PDE10A inhibitor with IC50 value of 1-1.3nM. It demonstrates excellent pharmacokinetic properties in multiple preclinical animal species. It has the potential to impact multiple symptomatic domains of schizophrenia including positive symptoms and cognitive impairment.

4.5 *For Research Use Only! Not for Human Use. We Do Not Sell to Patients.

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Product Details of THPP-1

CAS No. :1257051-63-0
Formula : C23H21ClN6O3
M.W : 464.90
SMILES Code : O=C(N1CCC2=NC(C3=CC=C(Cl)N=C3)=NC(OCCOC)=C2C1)C4=C5C=CC=CN5C=N4
English Name :(2-(6-Chloropyridin-3-yl)-4-(2-methoxyethoxy)-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl)(imidazo[1,5-a]pyridin-1-yl)methanone
MDL No. :N/A

Safety of THPP-1

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.15mL

0.43mL

0.22mL

10.76mL

2.15mL

1.08mL

21.51mL

4.30mL

2.15mL

 

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